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Acid-base imbalances - metabolic acidosis and alkalosis

By: HWC, Views: 7798

• Metabolic acidosis typically results from very low HCO3- ion blood concentrations. • Metabolic alkalosis typically results from very high HCO3- ion blood concentrations.

Definition of heart rate

By: HWC, Views: 7857

• Heart rate is determined by the rate of depolarizations of the sinoatrial (SA) node. • Cardiac output is directly proportional to heart rate, the greater the heart rate the greater the cardiac output. • Changes in heart rate are associated with exercise, stress or injury. Nervous ...

Griffith's experiments

By: HWC, Views: 4863

In the late 1920s, Fred Griffith was attempting to develop a vaccine against a bacterium that causes pneumonia. To find out why two strains of the bacteria differed in their deadliness, he injected mice with four different mixtures. Mice injected with R cells remained healthy. When Griffith ex...

Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation

By: HWC, Views: 8899

• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...

Mechanisms of capillary exchange

By: HWC, Views: 7876

■ The primary role of capillaries is to permit the exchange of nutrients and wastes between the blood and tissue cells (via interstitial fluid). ■ Oxygen and nutrients move from the blood to the cells. ■ Carbon dioxide and other wastes move from the cells to the blood. The three ba...

Introduction to filtration - filtrate formation and composition

By: HWC, Views: 7910

• At the nephron, the three process responsible for the formation of urine include: • Glomerular filtration. • Tubular reabsorption. • Tubular secretion. • During filtration, a filtrate is formed within the renal tubule. • Reabsorption is the conserving of water and many s...

Introduction to Pre-eclampsia

By: Administrator, Views: 10754

Pre-eclampsia (PE) is a disorder of pregnancy characterized by the onset of high blood pressure and often a significant amount of protein in the urine. When it arises, the condition begins after 20 weeks of pregnancy. In severe disease there may be red blood cell breakdown, a low blood platelet c...

Introduction to Insulin

By: Administrator, Views: 11822

The islets of Langerhans are composed of three major types of cells: Alpha cells secrete glucagon, elevating blood sugar. Beta cells secrete insulin, maintaining normal blood sugar. Delta cells secrete somatostatin, which suppresses release of glucagon and insulin. Hyposecretion or inadequa...

Mechanisms of capillary exchange (transcytosis & bulk flow)

By: HWC, Views: 7399

■ This method of capillary exchange is mainly used to transport small amounts of large, lipid-insoluble (water soluble) molecules, such as large proteins. ■ Substances, packaged in vesicles, move through endothelial cells via endocytosis and exocytosis. ■ This method of exchange is th...