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Helper T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 7810

• Most cells which have CD4 on their surface become Helper T cells (TN cells). • The CD4 1 cells only recognize a foreign antigen when it is presented with an antigen presenting immune cell (APC) that includes MHC-II protein. • The Helper T cell antigen receptor must match the presented...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 8030

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

B cells and antibodies

By: HWC, Views: 8510

What Are Antibodies? Antibodies, also known as immunoglobulins, are Y-shaped proteins that are produced by the immune system to help stop intruders from harming the body. When an intruder enters the body, the immune system springs into action. These invaders, which are called antigens, can be vi...

Bone elongation - processes at the epiphyseal plate

By: HWC, Views: 7967

• Interstitial lengthening occurs in only certain bones, primarily those of the appendages. • Such lengthening takes place at the epiphyseal plate, a layer of hyaline cartilage in the metaphysis of a growing bone. 1. Zone of resting cartilage. • Consisting of a hyaline cartilage pa...

Red Blood Cells - Erythropoietin (EPO)

By: HWC, Views: 7711

• The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone aft...

Embryonic development - week 1 and 2

By: HWC, Views: 7687

The first through eighth weeks after fertilization are called the embryonic. Week 1 • Within a day, the zygote begins mitotic cell division (cleavage) forming blastomeres. By the 4th day, the blastomeres have formed a solid ball called a morula. • The morula enters uterine cavity ar...

Uterine (menstrual) cycle - phases

By: HWC, Views: 7707

• The uterus goes through a cyclical developmental pattern to be ready for implantation and support of an embryo. • The uterine, or menstrual, cycle is under the control of ovarian horrnones. • The uterine cycle also has three phases: • Menstrual phase • Proliferative phase â€...

Primary and secondary response to infection

By: HWC, Views: 7470

• Pathogens enter the body by penetrating the non-specific barriers in the skin and mucus membranes. • Pathogens first encounter macrophages and natural killer cells that carry out phagocytosis and cytolysis respectively. • A pathogen's first encounter with the immune system can promo...

T cell receptors

By: HWC, Views: 7400

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...