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Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 8030

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

Cell mediated immune response to a viral infection Animation

By: HWC, Views: 3747

Intracellular pathogens are the targets of cell-mediated immune response. The process begins when a virus infects a macrophage. Another macrophage engulfs the same virus or an antigen from it. In both cells, enzymes cleave the viral antigens into small bits. The fragments move to the cell sur...

Immune responses Animation

By: HWC, Views: 4543

Overview of interactions in antibody-mediated and cell-mediated immunity Animation The antibody mediated immune response begins when a naive B cell encounters antigens from a pathogen, such as a bacterium. The B cell binds, processes, and displays this antigen. It is now an antigen-presenti...

T cell receptors

By: HWC, Views: 7400

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...

Nervous pathway to the Neuromuscular (NMJ)

By: HWC, Views: 8257

• A nervous impulse, also called an action potential, starts from the brain or spinal cord to signal skeletal muscle cell contraction. Action potentials continue along a motor neuron to the muscle cell. • The signal to contract must cross a synapse - the neuromuscular junction (NMJ) - betwe...

Conduction of action potentials

By: HWC, Views: 7884

• Action potentials must be rapidly conducted over long distances in order for the nervous system to communicate with other cells. • Propagation of an action potential uses processes similar to those that generate the potential at the trigger zone. • a When a graded potential reaches ...

Action potentials - electrical characteristics and generation

By: HWC, Views: 7567

• An action potential is the nervous impulse or signal for long distance communication. Each action potential is generated at the cell's trigger zone. • Action potentials are considered an all-or-nothing phenomena because they are either generated or not. • The generation of an action...

Phases of an Action Potential - Resting Potential, Threshold, Rising, Falling, & Recovery Phases

By: HWC, Views: 7138

In this tutorial, we will review the phases of an action potential measured from a small area of a neuron's membrane. The action potential can be divided into five phases: the resting potential, threshold, the rising phase, the falling phase, and the recovery phase. When the neuron is at rest,...

Depolarization of the SA node, Action potentials of the myocardium & ANS effects

By: HWC, Views: 7626

• A typical contractile cell in the myocardium has a resting membrane potential. • The resting membrane potential of cells in the SA node is not fixed, and is known as the pacemaker potential. • The action potential of a healthy SA nodal cell has three parts: • Pacemaker potential: ...