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Helper T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 7826

• Most cells which have CD4 on their surface become Helper T cells (TN cells). • The CD4 1 cells only recognize a foreign antigen when it is presented with an antigen presenting immune cell (APC) that includes MHC-II protein. • The Helper T cell antigen receptor must match the presented...

Immune responses Animation

By: HWC, Views: 4568

Overview of interactions in antibody-mediated and cell-mediated immunity Animation The antibody mediated immune response begins when a naive B cell encounters antigens from a pathogen, such as a bacterium. The B cell binds, processes, and displays this antigen. It is now an antigen-presenti...

T cell receptors

By: HWC, Views: 7424

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...

Cell mediated immune response to a viral infection Animation

By: HWC, Views: 3760

Intracellular pathogens are the targets of cell-mediated immune response. The process begins when a virus infects a macrophage. Another macrophage engulfs the same virus or an antigen from it. In both cells, enzymes cleave the viral antigens into small bits. The fragments move to the cell sur...

HIV Infection: Viral life cycle

By: HWC, Views: 7086

The series of steps that HIV follows to multiply in the body. The process begins when HIV encounters a CD4 cell. The seven steps in the HIV life cycle are: 1) binding; 2) fusion; 3) reverse transcription; 4) integration; 5) replication; 6) assembly; and 7) budding. Many viruses f...

B cells and antibodies

By: HWC, Views: 8523

What Are Antibodies? Antibodies, also known as immunoglobulins, are Y-shaped proteins that are produced by the immune system to help stop intruders from harming the body. When an intruder enters the body, the immune system springs into action. These invaders, which are called antigens, can be vi...

Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 7009

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Introduction to Human Immunodeficiency Virus (HIV)

By: Administrator, Views: 10649

Human immunodeficiency virus gains entry into helper T cells, uses the cell DNA to replicate, interferes with normal function of the T cells, and destroys the normal cells. 1 in 10 persons with AIDS: age 50 or older. 4% of all AIDS cases: age 65 or older. AIDS’ main form of treatment: an...

Autonomic Nervous System Animation

By: Administrator, Views: 11004

Parasympathetic Division Works to conserve energy and innervate the digestive system. When activated, it: stimulates the salivary and digestive glands. decreases the metabolic rate. slows the heart rate. reduces blood pressure. promotes the passage of material through the intestines along...