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Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 7001

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Nervous pathway to the Neuromuscular (NMJ)

By: HWC, Views: 8257

• A nervous impulse, also called an action potential, starts from the brain or spinal cord to signal skeletal muscle cell contraction. Action potentials continue along a motor neuron to the muscle cell. • The signal to contract must cross a synapse - the neuromuscular junction (NMJ) - betwe...

Parathyroid hormone (bone resorption) & Calcitonin (bone deposition)

By: HWC, Views: 7692

• Cellular needs for calcium may cause blood calcium concentrations to decline below the normal range. • This decrease stimulates cells in the parathyroid gland to secrete parathyroid hormone. • Binding of parathyroid hormone to osteoclasts in bone tissue promotes bone resorption and th...

Transmission Across a Synapse

By: Administrator, Views: 5936

Transmission Across a Synapse

Pores and Ion Channels

By: HWC, Views: 6906

Transmembrane channels, also called membrane channels, are pores within a lipid bilayer. The channels can be formed by protein complexes that run across the membrane or by peptides. They may cross the cell membrane, connecting the cytosol, or cytoplasm, to the extracellular matrix. Membrane po...

Membrane transport proteins - pores, gated channels and pumps

By: HWC, Views: 7842

• a Three different types of membrane ion transport proteins are required to produce and carry electrical signals: • Pores • Gated channels • Na+/ K+ pump • Pores are always open and allow the diffusion of Na+ and K+ ions across the membrane, down their concentration gradients...

Phases of an Action Potential - Resting Potential, Threshold, Rising, Falling, & Recovery Phases

By: HWC, Views: 7138

In this tutorial, we will review the phases of an action potential measured from a small area of a neuron's membrane. The action potential can be divided into five phases: the resting potential, threshold, the rising phase, the falling phase, and the recovery phase. When the neuron is at rest,...

Simple Diffusion - Ion transport

By: HWC, Views: 7743

In the process of diffusion, a substance tends to move from an area of high concentration to an area of low concentration until its concentration becomes equal throughout a space. Ions must diffuse through membrane pores or gated channels. Pores are always open. More pores allow more ions...

Exocytosis - secretion

By: HWC, Views: 7738

Exocytosis is another method of vesicular transport that moves large volumes Of fluid or chemicals out of the cell. It is a process by which a cell transports secretory products through the cytoplasm to the plasma membrane. A examples of cellular secretory products: 1. Secreted protein - enzym...