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Types of antimicrobial substances (interferons & complement protein)

By: HWC, Views: 7746

• Found in blood and interstitial fluids. • Discourage microbial growth. • Include interferon and complement proteins. • Produced and released by virus-infected lymphocytes. • Enter new cells and inhibit viral replication. • Act against a large variety of viruses (non-speci...

Primary and secondary response to infection

By: HWC, Views: 7470

• Pathogens enter the body by penetrating the non-specific barriers in the skin and mucus membranes. • Pathogens first encounter macrophages and natural killer cells that carry out phagocytosis and cytolysis respectively. • A pathogen's first encounter with the immune system can promo...

Role of complement proteins

By: HWC, Views: 7473

• Non-specific and specific defense mechanisms work through the functions of complement proteins. • As soon as pathogens penetrate the physical barrier of the skin, other resistance mechanisms begin. • Cells, such as macrophages, phagocytize pathogens. • These cells increase exposu...

Cellular defenses (natural killer cells, phagocyte types & process of phagocytosis)

By: HWC, Views: 7457

• Lymphocytes that rapidly defend against abnormal (cancer) or virus-infected cells. • Found in blood, spleen, lymph nodes, and red bone marrow. • Lack receptors for binding with specific antigens. • Act upon cells displaying abnormal MHC antigens. • NK cells destroy cells in ...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 8030

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...