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Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 7001

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Molecules, Membrane Permeability and Structure

By: HWC, Views: 7186

Organisms are not isolated system at equilibrium and need to intake nutrients and electrolytes as remove wastes. Similarly Cells within an organism must also exchange compound by passing them through membrane. The permeability of a membrane is the rate of passive diffusion of molecules th...

Lipid digestion - mouth, stomach and small intestine

By: HWC, Views: 7784

• Lipid digestion takes place primarily in the small intestine; some occurs in the mouth and stomach. • Lipases are enzymes that break down triglycerides and phospholipids. • Lingual and gastric lipases hydrolyze a small amount of triglycerides. • End products are fatty acids and...

Simple Diffusion - gases and nonpolar compounds transport

By: HWC, Views: 8037

Gases and some molecules can diffuse through the phospholipid bilayer because they are small or non-polar. Oxygen gas. Carbon dioxide gas. Lipid based hormones. Plasma membranes are selectively permeable: The lipid bilayer is always permeable to small, nonpolar, uncharged molecules ...

Mechanisms of capillary exchange

By: HWC, Views: 7876

■ The primary role of capillaries is to permit the exchange of nutrients and wastes between the blood and tissue cells (via interstitial fluid). ■ Oxygen and nutrients move from the blood to the cells. ■ Carbon dioxide and other wastes move from the cells to the blood. The three ba...

Complement Proteins Animation

By: HWC, Views: 4479

Formation of membrane attack complexes. Complement proteins can activate when they bind to antibodies that are bound to a pathogen. Complement proteins also activate when they bind directly to bacterial surfaces. Cascading reactions yield huge numbers of different types of complement protei...

Lipid catabolism - lipolysis and beta oxidation and oxidation of fatty acids

By: HWC, Views: 7962

• Digestion hydrolyzes lipids into fatty acids and glycerol. • Fatty acids and glycerol are: • Oxidized to generate ATP. • Used to produce triglycerides that are stored as energy reserves in adipose tissue. • Lipid catabolism begins with lipolysis in which lipids are broken do...

Lipid catabolism ( ketogenesis and oxidation of glycerol) and Lipid anabolism (lipogenesis)

By: HWC, Views: 8029

• During excessive beta oxidation, the two-carbon fatty acid fragments are converted into acidic ketone bodies. • Ketosis, the overproduction of ketone bodies, can lead to acidosis (ketoacidosis) of the blood. • After lipolysis, glycerol is converted to pyruvic acid. • Pyruvic aci...

Lipid absorption - end products & transport mechanism

By: HWC, Views: 7253

• The end products, fatty acids and monoglycerides, depend on bile salts for absorption. • Bile salts form micelles (tiny spheres), which ferry fatty acids and monoglycerides to epithelial cells. • Free fatty acids, monoglycerides, and some phospholipids and cholesterol molecules, dif...