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Stroke volume - preload, sarcomere length and Frank -Starling law

By: HWC, Views: 7352

• Sarcomere length affects muscle tension and the force of contraction. • Increased muscle stretch (increased sarcomere length) at the beginning of contraction increases tension produced during the contraction. • A more forceful contraction ejects more blood, thus increasing stroke volu...

Factors that influence muscle tension - Sarcomere length and force, understretched and overstretched

By: HWC, Views: 7752

• Muscle tension generated through the contraction of muscle cells provides the force necessary for the muscular system to function. • The amount of tension produced depends on several factors: • Sarcomere length Frequency of stimulation • Motor unit size • Recruitment of moto...

Stroke volume

By: HWC, Views: 7723

Preload definition • Preload is the degree of stretch of cardiac muscles cells prior to contraction. • The amount of stretch is related to the end-diastolic volume[EDV]. • Increased return blood flow from the veins increases end-diastolic volume. Cardiac muscle sarcomeres stretch and ...

Definitions of stroke volume, preload definition & Factors influencing stroke volume

By: HWC, Views: 7510

• Stroke volume is directly correlated with cardiac output-the greater the stroke volume the greater the cardiac output. • Stroke volume represents the difference in the amount of blood between: • the volume in the ventricles at the end of diastole (end-diastolic volume EDV); • the ...

Contraction cycle of a sarcomere

By: HWC, Views: 8178

• A single nervous signal releases Ca2+ ions into the sarcoplasm and initiates the contraction cycle. step 1. ATP hydrolysis • ATP provides the to move myosin molecules back into the energized configuration necessary to perform the power stroke. Step 2. Crossbridge attachment • Myosin...

Muscle cell structures - actin, myosin and titin filaments

By: HWC, Views: 7876

Once the muscle cell has been excited it will contract. • A muscle action potential will trigger the release Of Ca2+ ions into the sarcoplasm. • The Ca2+ ions bind to the regulatory proteins and trigger contraction. • Within skeletal muscle cells are structures that provide the ability...

The primary factors that affect circulation - MABP, CO and SVR

By: HWC, Views: 8047

Introduction Blood flow is determined by the relative intensities of factors that drive and resist moving blood. • Cardiac output (CO) equals the mean arterial blood pressure (MABP, a driving force) divided by systemic vascular resistance (SVR, a resisting force). • Hormones and the cen...

Properties of macromolecules (Explained with No Audio)

By: HWC, Views: 6679

The term thermoplast refers to a plastic, which when heated is soft and deformable, but which rehardens when cooled. The molecular structure of the macromolecules is comparable to a cotton ball in which the individual fibers of the macromolecules are shown. The fibers of the cotton ball can s...

Stroke volume - afterload definition & hypertension

By: HWC, Views: 7190

• Pressure (or other resisting force) that ventricles must overcome to push open semilunar valves and eject blood. ▪ Normally, the left ventricle blood pressure must overcome arterial pressure in the aorta. ▪ Abnormally high blood pressure, or hypertension, increases aortic pressure w...