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Cellular defenses (natural killer cells, phagocyte types & process of phagocytosis)

By: HWC, Views: 7474

• Lymphocytes that rapidly defend against abnormal (cancer) or virus-infected cells. • Found in blood, spleen, lymph nodes, and red bone marrow. • Lack receptors for binding with specific antigens. • Act upon cells displaying abnormal MHC antigens. • NK cells destroy cells in ...

Erythropoietin (EPO)

By: HWC, Views: 7245

■ Secreted by kidney cells when blood oxygen is low. ■ Targets cells in red bone marrow that will become red blood cells. ■ Promotes increased numbers of mature red blood cells. ■ More mature red blood cells carry more oxygen so blood oxygen level is restored to normal.

T cell receptors

By: HWC, Views: 7426

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 8056

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

Cardiac conductile cells

By: HWC, Views: 7983

• In order for the heart to function properly, all of its cells must contract in a specific sequence. This sequence is determined by a pathway known as the conduction system. • Cardiac muscle cells have two attributes that enable the conduction system to work: • Connective. Action pot...

Griffith's experiments

By: HWC, Views: 4878

In the late 1920s, Fred Griffith was attempting to develop a vaccine against a bacterium that causes pneumonia. To find out why two strains of the bacteria differed in their deadliness, he injected mice with four different mixtures. Mice injected with R cells remained healthy. When Griffith ex...

Cell mediated immune response to a viral infection Animation

By: HWC, Views: 3761

Intracellular pathogens are the targets of cell-mediated immune response. The process begins when a virus infects a macrophage. Another macrophage engulfs the same virus or an antigen from it. In both cells, enzymes cleave the viral antigens into small bits. The fragments move to the cell sur...

Introduction to Insulin

By: Administrator, Views: 11841

The islets of Langerhans are composed of three major types of cells: Alpha cells secrete glucagon, elevating blood sugar. Beta cells secrete insulin, maintaining normal blood sugar. Delta cells secrete somatostatin, which suppresses release of glucagon and insulin. Hyposecretion or inadequa...

Helper T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 7829

• Most cells which have CD4 on their surface become Helper T cells (TN cells). • The CD4 1 cells only recognize a foreign antigen when it is presented with an antigen presenting immune cell (APC) that includes MHC-II protein. • The Helper T cell antigen receptor must match the presented...