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The life cycle of protein

By: HWC, Views: 7351

The life cycle of a typical protein begins with its synthesis on a ribosome. As the polypeptide chain grows, molecules of a chaperone protein bind along its length. This prevents misfolding of the nascent polypeptide. ATP binding causes chaperone release. For most proteins, the polypeptide th...

Structure of a Ribosome

By: HWC, Views: 4607

The structure and function of the mammalian ribosome. The mammalian ribosome consists of two subunits, one small and one large. Each subunit is assembled in the nucleus from rRNA and structural proteins. Once assembled, the ribosomal subunits are shipped separately to the cytoplasm. ...

The 4 steps of translation Animation

By: HWC, Views: 3547

Translation is the process of formation of a polypeptide chain according to codon present in mRNA. The four steps of translation are: Activation or charging of tRNA Initiation – recognition of start codon, binding of ribosomal subunits to mRNA and formation of initiation complex with Met-tR...

Protein Secondary and Tertiary Structures - Animation

By: HWC, Views: 3899

Amino acid sequence dictates a protein's final shape. The presence of certain amino acids favors a pattern of hydrogen bonding that causes part of the polypeptide chain to coil and twist into an alpha helix. The presence of other amino acids enables hydrogen bonding between strand like r...

Mitochondrial Structure & ETC Protein Complexes (Protein Complexes and Electron Transport)

By: HWC, Views: 7336

The energy carrying molecules, NADH and FADH2, that were generated in glycolysis and the Krebs cycle, now are processed in the mitochondria where their high energy electrons are deposited in an electron chain complex located in the inner mitochondrial membranes. These high-energy electrons now dr...

Cellular Respiration & Glucose Mobilization (Glucose transport & Phosphorylation of Glucose)

By: HWC, Views: 7522

Glucose is completely broken down into CO2 and H2O during the process of cellular respiration, which includes 3 stages: 1) glycolysis; 2) the Krebs Cycle; and 3) the electron transport chain. Glucose enters this energy yielding pathway of cellular respiration in the first stage known as...

Summary of glucose catabolism

By: HWC, Views: 7975

■ The complete oxidation of one glucose molecule produces the following ATP molecules in each step. • Glycolysis; • Formation of acetyl CoA; • Krebs cycle; • Electron transport chain. ■ In addition, glucose catabolism produces six CO2 molecules and water.

Polymerase chain reaction PCR - Animation

By: HWC, Views: 1594

Polymerase chain reaction (PCR) is a method that amplifies fragments of DNA. The purpose of PCR is to create copies of a specific region of DNA. To use this technique, researchers must know the base sequences at either end of the region of interest. They use this information to create...

Protein Structure - Primary, Secondary, Tertiary and Quaternary

By: HWC, Views: 7654

A protein's first order structure, or primary structure, begins with the amino acid sequence of the polypeptide chain. The 20 different amino acids can be arranged in an infinite number of sequences. For example, the hormone insulin, which regulates the uptake of glucose from the blood into ce...