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Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation

By: HWC, Views: 8914

• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...

Medullary osmotic gradient - influencing factors

By: HWC, Views: 8069

▪ Maintenance of fluid volume and composition, despite changes in water input and output, is crucial to a healthy life. ▪ Regulation of blood's osmolarity, or solute concentration, is a function of the nephron. • Normal osmolarity is maintained by the ability of the nephron to alter uri...

Medullary osmotic gradient: countercurrent multiplier, urea recycling & vasa recta countercurrent exchange

By: HWC, Views: 8444

▪ The primary cause of the medullary osmotic gradient is the active transport of solutes. • In the ascending limb of the loop, active transport of Na+ ions drives passive reabsorption of Cl- ions. • Addition of these ions to the interstitial fluid of the medulla increases its osmolarity...

Forming urine ( influencing factors), Forming dilute urine & Forming concentrated urine

By: HWC, Views: 8226

• The amount of urine produced by the nephron depends on : • Body fluid volume. • Body fluid composition. • Dilute urine is formed when the body is normally hydrated. • The medullary osmotic gradient determines the osmolarity of the filtrate. • Filtrate osmolarity increase...

Neuron structure and function - sensory neurons, association neurons & motor neurons

By: HWC, Views: 7669

• The primary function of the nervous system is to provide rapid communication within the body to maintain homeostasis. • This function underlies behaviors, thinking and control of organ functions. • The basic functions of the nervous system are provided by: • Sensory neurons • ...

System organization - PPM system types (Somatic, Autonomic & Enteric) and Reflex arc types

By: HWC, Views: 7875

• The PNS consists of all nervous tissue outside of the CNS. • It is divided into three functional components: • Somatic nervous system (SNS) • Autonomic nervous system (ANS) • Enteric nervous system (ENS) • The SNS consists of: • Sensory neurons from skeletal muscles ...

Requirements for nervous signals

By: HWC, Views: 7689

• The function of neurons is to allow communication between cells, thereby maintaining homeostasis. • Electrical signals, called membrane potentials, travel along the membranes of the neurons. • Voltage variability and distance traveled determine the type of nervous signal. 1. Graded...

Membrane transport proteins - pores, gated channels and pumps

By: HWC, Views: 7859

• a Three different types of membrane ion transport proteins are required to produce and carry electrical signals: • Pores • Gated channels • Na+/ K+ pump • Pores are always open and allow the diffusion of Na+ and K+ ions across the membrane, down their concentration gradients...

Resting membrane potential - electrical polarity and maintenance requirements

By: HWC, Views: 7474

• A resting membrane potential exists when there is a buildup of: 1. positive ions outside the membrane. 2. negative ions inside the membrane. • Membranes with opposing charges are said to be polarized. • The difference in charge applies only to the small distance across the membran...