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Epinephrine/NE (heart rate, altered blood flow, glycogenolysis & bronchodilation)

By: HWC, Views: 7717

• Stressors trigger increased sympathetic stimulation from the hypothalamus to the chromaffin cells of the adrenal medulla. • This causes the immediate release of epinephrine and norepinephrine (NE). • Epinephrine/NE binds to the cardiac muscles of the heart. • Cardiac muscle cells ...

Cortisol (protein catabolism, gluconeogenesis, vasoconstriction & anti-inflammation)

By: HWC, Views: 7356

• Stressors stimulate production of hypothalamic releasing hormones, corticotropin releasing hormone, hormone (CRH) and adrenocorticotropic hormone (ACTH) stimulate. • These hormones promote increased production of 1 cortisol from the zona fasciculata cells of the adrenal cortex. • Cort...

Types of disease resistance: innate defenses & immunity

By: HWC, Views: 8010

Our immune system protects us and helps fight off disease. Microorganisms, small microscopic organisms, and viruses are everywhere. Ever thought about how many are on that door you just opened? Many microbes and viruses can cause disease and are termed pathogens. Plants and animals have what i...

Role of complement proteins

By: HWC, Views: 7539

• Non-specific and specific defense mechanisms work through the functions of complement proteins. • As soon as pathogens penetrate the physical barrier of the skin, other resistance mechanisms begin. • Cells, such as macrophages, phagocytize pathogens. • These cells increase exposu...

Primary and secondary response to infection

By: HWC, Views: 7523

• Pathogens enter the body by penetrating the non-specific barriers in the skin and mucus membranes. • Pathogens first encounter macrophages and natural killer cells that carry out phagocytosis and cytolysis respectively. • A pathogen's first encounter with the immune system can promo...

Non-specific disease resistance mechanisms & Skin's defense barriers

By: HWC, Views: 7768

• Non-specific disease resistance acts quickly to fight a wide variety of invaders. • Mechanisms include: • Barriers • Antimicrobial substances • Cellular defenses • Inflammation • Fever Barriers - types • Physical and chemical bathers prevent invasion by micro...

Barriers - eye structures, digestive mucosa, respiratory mucosa & genitourinary mucosa

By: HWC, Views: 8085

• Eyebrows, eyelids, eyelashes and conjunctiva serve to trap microbes preventing their invasion. • Tearing (lacrimation) is a protective mechanism that washes away microbes that attempt to enter the eyes. • Salts, mucus, and lysozymes in tears neutralize substances and bacteria. â€...

Types of antimicrobial substances (interferons & complement protein)

By: HWC, Views: 7807

• Found in blood and interstitial fluids. • Discourage microbial growth. • Include interferon and complement proteins. • Produced and released by virus-infected lymphocytes. • Enter new cells and inhibit viral replication. • Act against a large variety of viruses (non-speci...

Inflammation and Fever

By: HWC, Views: 8258

• Inflammation is an immune response that can occur anywhere in the body, but is observed most frequently on the skin. • It provides early protection by preventing infection from spreading to other parts of the body. • Inflammation also promotes repair of damaged tissues. Inflammat...

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