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Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 7002

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Enzyme-Catalyzed Reactions

By: HWC, Views: 7180

S P Substrate in great excess ([S] -- [E]) (More correctly [S] -- KM, but more on this later) Zero order rate equation: v = k where k is the zero-order rate constant (with respect to substrate). (More correctly [S] -- KM, but more on this later) Substrate forms complex with enzyme. ...

Role of complement proteins

By: HWC, Views: 7474

• Non-specific and specific defense mechanisms work through the functions of complement proteins. • As soon as pathogens penetrate the physical barrier of the skin, other resistance mechanisms begin. • Cells, such as macrophages, phagocytize pathogens. • These cells increase exposu...

Chemical Synapse Animation

By: HWC, Views: 5095

A neuromuscular junction is a chemical synapse between the axon endings of a motor neuron and a muscle cell. A narrow synaptic cleft separates the presynaptic cell (the motor neuron) from the postsynaptic cell (the muscle cell). The presynaptic cell contains vesicles filled with neurotransmitt...

Osmosis - Isotonic, Hypotonic, and Hypertonic​ Solutions

By: HWC, Views: 7824

Isotonic: Equal Water moves in and out of the cell at an equal rate. The cell remains unchanged. Hypotonic: "hypo" hippo Water moves into the cell, making it swell and get fat (like a hippo). Eventually the cell can rupture and burst (aka lyse). Hypertonic: "like a raisin" Water leaves...

Haustral churning, Gastrocolic reflex and mass peristalsis & Defecation

By: HWC, Views: 7902

• As the cecum becomes filled and distends, a local reflex causes: • Closure of the ileocecal valve. • Activation of haustral churning. • Haustral churning mixes the chyme, which helps absorption of water, salts, and vitamins. • Haustral churning propels the contents of the colo...

Sickle Cell Anemia

By: Administrator, Views: 10770

The clinical manifestations of sickle cell anemia result from pathologic changes to structures and systems throughout the body.

Type of Cell Junctions - Desmosome, Hemidesmosomes and Gap Junctions

By: HWC, Views: 8073

Cell Junctions: Cell junctions are found in some multi-cellular organisms. They exist of complexes and are found between cells and between cells and other structures. The junctions provide a way for cells to connect and exchange signals. What are tight junctions, desmosomes, and gap junctions...

Hormonal feedback loop components

By: HWC, Views: 7830

The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: ■ Stimulus - a change in a body condition. ■ Production cell - an endocrine cell that produces a hormone after b...