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Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 7001

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Protein catabolism (Krebs cycle) and Protein anabolism (protein synthesis)

By: HWC, Views: 8169

• Deaminated acids are brought into the Krebs cycle to be oxidized to CO2 and H2O. • Before entering the Krebs cycle, the deaminated acids are converted into intermediate products (pyruvic acid, acetyl coenzyme A, carbonic acids). • In the Krebs cycle, amino acids are oxidized to form r...

Introduction to Sleep Apnea

By: Administrator, Views: 10543

Apnea is the cessation of breathing. During apnea, there is no movement of the muscles of inhalation, and the volume of the lungs initially remains unchanged. Depending on how blocked the airways are (patency), there may or may not be a flow of gas between the lungs and the environment; gas excha...

Endocrine System Animation

By: Administrator, Views: 1421

Vital function of endocrine system: Production and regulation of chemical substances called hormones. Hormones Chemical transmitters released in small amounts and transported via bloodstream to a target organ or other cells. Transfer information and instructions from one set of cells to anot...

Cellular defenses (natural killer cells, phagocyte types & process of phagocytosis)

By: HWC, Views: 7458

• Lymphocytes that rapidly defend against abnormal (cancer) or virus-infected cells. • Found in blood, spleen, lymph nodes, and red bone marrow. • Lack receptors for binding with specific antigens. • Act upon cells displaying abnormal MHC antigens. • NK cells destroy cells in ...

Cellular Defects - Osteoblasts, Osteoclasts and Osteocytes

By: HWC, Views: 7324

■ Metabolically active bone-building cells that secrete astroid. ■ Cover surfaces of newly formed bone and respond to growth stimuli ■ Less responsive to growth factors as the body ages. ■ Contribute to hone loss once their reproductive and biosynthetic potential lessens....

Parathyroid hormone (bone resorption) & Calcitonin (bone deposition)

By: HWC, Views: 7692

• Cellular needs for calcium may cause blood calcium concentrations to decline below the normal range. • This decrease stimulates cells in the parathyroid gland to secrete parathyroid hormone. • Binding of parathyroid hormone to osteoclasts in bone tissue promotes bone resorption and th...

How proteins function? How do proteins work?

By: HWC, Views: 7381

How proteins function is really about how proteins "do work" in cells. How do proteins work? Let's start thinking about protein function by looking at something important to you: your hair. Keratin is a structural protein that is composed of 2 intertwined or helical strands. Keratin is also f...

Transcription—A molecular view

By: HWC, Views: 3310

Transcription, as related to genomics, is the process of making an RNA copy of a gene's DNA sequence. This copy, called messenger RNA (mRNA), carries the gene's protein information encoded in DNA. During transcription, a DNA molecule is copied into RNA molecules that are then used to translate...