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Hormonal feedback loop components & Glucagon (glycogenolysis and gluconeogenesis)

By: HWC, Views: 8180

The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after ...

ACTH/Cortisol (glycogenolysis, protein catabolism, lipolysis and gluconeogenesis)

By: HWC, Views: 8234

• A decline in blood glucose concentration stimulates corticotropic cells in the anterior pituitary to produce adrenocorticotropic hormone (ACTH). • ACTH binds with cells in the zona fasciculata of the adrenal cortex. • Increased ACTH promotes the production of cortisol, the major gluco...

Insulin (glucose uptake by body cells), glycogenesis and lipogenesis

By: HWC, Views: 8477

Insulin is the regulator that allows the sugar from the foods we eat (be it a piece of cake or a stick of celery) to enter our tissues and become part of the metabolic process. Insulin is made by the Islets of Langerhans, which are found in the pancreas of every person. As we previously mentio...

Parathyroid hormone (bone resorption) & Calcitonin (bone deposition)

By: HWC, Views: 8309

• Cellular needs for calcium may cause blood calcium concentrations to decline below the normal range. • This decrease stimulates cells in the parathyroid gland to secrete parathyroid hormone. • Binding of parathyroid hormone to osteoclasts in bone tissue promotes bone resorption and th...

Antidiuretic hormone (vasoconstriction, water reabsorption & sweat inhibition)

By: HWC, Views: 8277

• Dehydration, blood loss, and low amounts of water in the blood can cause blood volume and pressure to decrease. • Neurosecretoxy cells in the posterior pituitary release antidiuretic hormone(ADH). • ADH binds to smooth muscle cells in blood vessel walls, stimulating them to vasoconstr...

Renin/Angiotensin (water gain from urine & Na ion and water reabsorption)

By: HWC, Views: 8259

• Sensing declining blood pressure or blood volume, juxtaglomerular cells of the nephron release renin, an enzyme that promotes the formation of angiotensin II. • Angiotensin II targets smooth muscle cells in blood vessels that provide blood to the nephron. • Angiotensin II causes thes...

Atrial natriuretic peptide (vasodilation) & Aldosterone

By: HWC, Views: 8000

• Certain situations will cause the body's stress level to rise. • increased blood pressure will stretch the atria of the heart, stimulating the secretion of atria natriuretic peptide (MP). • ANP causes muscle cells in blood vessels to relax. • Blood pressure is lowered as a result ...

TRH/TSH/Thyroid hormone

By: HWC, Views: 7911

Thyroid hormone production • A decline in metabolic rate caused by increased metabolic need or physical exertion stimulates the production of thyrotropin hormone releasing (TRH) hormone from the cells of the hypothalamus. • Thyrotropin hormone releasing hormone targets the thyrotrophic ce...

hGH (protein synthesis, growth and development)

By: HWC, Views: 8754

• Increased GHRH, a hypothalamic releasing hormone stimulated by low blood glucose, physical exertion, and increased sympathetic stimulation, stimulates the production of human growth hormone (hGH) from the somatotrophic cells of the anterior pituitary. • Human growth hormone targets cartil...