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Michaelis–Menten equation & Kinetic parameters

By: HWC, Views: 7506

The Michaelis–Menten equation is the rate equation for a one-substrate enzyme-catalyzed reaction. This equation relates the initial reaction rate (v0), the maximum reaction rate (Vmax), and the initial substrate concentration [S] through the Michaelis constant KM—a measure of the substrat...

Phases of an Action Potential - Resting Potential, Threshold, Rising, Falling, & Recovery Phases

By: HWC, Views: 7153

In this tutorial, we will review the phases of an action potential measured from a small area of a neuron's membrane. The action potential can be divided into five phases: the resting potential, threshold, the rising phase, the falling phase, and the recovery phase. When the neuron is at rest,...

Normal and abnormal blood pH

By: HWC, Views: 7790

• Dissociation of the chemical substances in the body fluids can result in the production of free hydrogen ions. • The pH scale is used to measure the concentration of hydrogen ions in solution. • Normal blood pH values vary around 7.4. • When hydrogen ion concentration increases, t...

Role of the respiratory system - effect of altered ventilation rates

By: HWC, Views: 7595

• Dissociation of the chemical substances in the body fluids can result in the production of free hydrogen ions. • The pH scale is used to measure the concentration of hydrogen ions in solution. • Normal blood pH values vary around 7.4. • When hydrogen ion concentration increases, t...

Heart sounds

By: HWC, Views: 7619

During a normal, healthy heartbeat, or what we call a cardiac cycle, the top two chambers of the heart, called the atria, contract simultaneously. Then, as they relax, the bottom two chambers, called the ventricles, contract. This explains what happens during a cardiac cycle, but what it doesn't ...

Muscle Fatigue and Recovery

By: HWC, Views: 7511

• After prolonged activity, muscle contraction weakens, and the muscle enters a state of fatigue. • Fatigue results from in muscle cells, such as: • Inadequate release of calcium ions • Depletion of energy sources • Lack of oxygen • Build up of lactic acid other metabolic w...

Depolarization of the SA node, Action potentials of the myocardium & ANS effects

By: HWC, Views: 7633

• A typical contractile cell in the myocardium has a resting membrane potential. • The resting membrane potential of cells in the SA node is not fixed, and is known as the pacemaker potential. • The action potential of a healthy SA nodal cell has three parts: • Pacemaker potential: ...

Homeostasis (range of body conditions, normal limits, mild stresses & severe stresses)

By: HWC, Views: 7701

Homeostasis: • Provides relative stability of the internal environment. • Results from constant adjustments. • Regulated by regulatory processes. • Requires system interplay. • Normal limits. • Temporary stresses. • Disruptions requiring medical intervention. • D...

Phases of mitosis

By: HWC, Views: 5685

Prophase is the first step in the mitotic process. During prophase, the chromosomes condense. The centrosomes begin to form a spindle and move into position on opposite sides of the cell. Sister chromatids are held together by a protein called cohesin at the centromere. Prometaphase is the sec...