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Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 5862

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Immune responses Animation

By: HWC, Views: 3512

Overview of interactions in antibody-mediated and cell-mediated immunity Animation The antibody mediated immune response begins when a naive B cell encounters antigens from a pathogen, such as a bacterium. The B cell binds, processes, and displays this antigen. It is now an antigen-presenti...

Autonomic Nervous System Animation

By: Administrator, Views: 9936

Parasympathetic Division Works to conserve energy and innervate the digestive system. When activated, it: stimulates the salivary and digestive glands. decreases the metabolic rate. slows the heart rate. reduces blood pressure. promotes the passage of material through the intestines along...

Helper T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 6739

• Most cells which have CD4 on their surface become Helper T cells (TN cells). • The CD4 1 cells only recognize a foreign antigen when it is presented with an antigen presenting immune cell (APC) that includes MHC-II protein. • The Helper T cell antigen receptor must match the presented...

T cell receptors

By: HWC, Views: 6329

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...

B cells and antibodies

By: HWC, Views: 7455

What Are Antibodies? Antibodies, also known as immunoglobulins, are Y-shaped proteins that are produced by the immune system to help stop intruders from harming the body. When an intruder enters the body, the immune system springs into action. These invaders, which are called antigens, can be vi...

Hormonal regulation of blood pressure - RAA system

By: HWC, Views: 7089

■ Long-term regulation of MABP is under hormonal control. • Hormones that affect blood pressure and volume: the renin-angiotensin-aldosterone (RAA) system, antidiuretic hormone (ADM), and atrial natriuretic peptide (ANP). ■ Most important hormonal regulator of MABP. Activated by drop in...

Role of complement proteins

By: HWC, Views: 6390

• Non-specific and specific defense mechanisms work through the functions of complement proteins. • As soon as pathogens penetrate the physical barrier of the skin, other resistance mechanisms begin. • Cells, such as macrophages, phagocytize pathogens. • These cells increase exposu...

Haustral churning, Gastrocolic reflex and mass peristalsis & Defecation

By: HWC, Views: 6769

• As the cecum becomes filled and distends, a local reflex causes: • Closure of the ileocecal valve. • Activation of haustral churning. • Haustral churning mixes the chyme, which helps absorption of water, salts, and vitamins. • Haustral churning propels the contents of the colo...