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Regulation of GFR: autoregulation via myogenic mechanism Myogenic mechanism

By: HWC, Views: 9198

• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Renal autoregulation occurs when...

Definitions of stroke volume, preload definition & Factors influencing stroke volume

By: HWC, Views: 7509

• Stroke volume is directly correlated with cardiac output-the greater the stroke volume the greater the cardiac output. • Stroke volume represents the difference in the amount of blood between: • the volume in the ventricles at the end of diastole (end-diastolic volume EDV); • the ...

Hormonal feedback loop components & Glucagon (glycogenolysis and gluconeogenesis)

By: HWC, Views: 7528

The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after ...

Rh blood type and complications during pregnancy & Fertilization

By: HWC, Views: 5081

Complications can arise if an Rh- woman is impregnated by an Rh+ man. The fetus maybe Rh+. During childbirth, some of the fetal Rh+ cells may leak into the maternal bloodstream. The woman's immune system views the Rh+ as foreign and makes antibodies against it. If the woman becomes pr...

Acid-base imbalances - metabolic acidosis and alkalosis

By: HWC, Views: 7798

• Metabolic acidosis typically results from very low HCO3- ion blood concentrations. • Metabolic alkalosis typically results from very high HCO3- ion blood concentrations.

Definition of heart rate

By: HWC, Views: 7857

• Heart rate is determined by the rate of depolarizations of the sinoatrial (SA) node. • Cardiac output is directly proportional to heart rate, the greater the heart rate the greater the cardiac output. • Changes in heart rate are associated with exercise, stress or injury. Nervous ...

Griffith's experiments

By: HWC, Views: 4864

In the late 1920s, Fred Griffith was attempting to develop a vaccine against a bacterium that causes pneumonia. To find out why two strains of the bacteria differed in their deadliness, he injected mice with four different mixtures. Mice injected with R cells remained healthy. When Griffith ex...

Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation

By: HWC, Views: 8900

• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...

Mechanisms of capillary exchange

By: HWC, Views: 7876

■ The primary role of capillaries is to permit the exchange of nutrients and wastes between the blood and tissue cells (via interstitial fluid). ■ Oxygen and nutrients move from the blood to the cells. ■ Carbon dioxide and other wastes move from the cells to the blood. The three ba...