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Glomerular filtrate rate: pressures that affect GFR, NFP & GFR and blood composition
By: HWC, Views: 8824
• The glomerular filtration rate is the amount of filtrate formed per minute within the renal corpuscle. • Once the filtrate is formed it moves down the tubule. • The production and movement of filtrate depends on three pressures: I. Glomerular blood hydrostatic pressure (GBHP) is ...
Regulation of GFR: three methods, autoregulation & autoregulation via myogenic mechanism
By: HWC, Views: 8831
• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Hormonal regulation. • Ren...
Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation
By: HWC, Views: 9506
• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...
Medullary osmotic gradient - influencing factors
By: HWC, Views: 8716
▪ Maintenance of fluid volume and composition, despite changes in water input and output, is crucial to a healthy life. ▪ Regulation of blood's osmolarity, or solute concentration, is a function of the nephron. • Normal osmolarity is maintained by the ability of the nephron to alter uri...
By: HWC, Views: 9092
▪ The primary cause of the medullary osmotic gradient is the active transport of solutes. • In the ascending limb of the loop, active transport of Na+ ions drives passive reabsorption of Cl- ions. • Addition of these ions to the interstitial fluid of the medulla increases its osmolarity...
Forming urine ( influencing factors), Forming dilute urine & Forming concentrated urine
By: HWC, Views: 8838
• The amount of urine produced by the nephron depends on : • Body fluid volume. • Body fluid composition. • Dilute urine is formed when the body is normally hydrated. • The medullary osmotic gradient determines the osmolarity of the filtrate. • Filtrate osmolarity increase...
Neuron structure and function - sensory neurons, association neurons & motor neurons
By: HWC, Views: 8284
• The primary function of the nervous system is to provide rapid communication within the body to maintain homeostasis. • This function underlies behaviors, thinking and control of organ functions. • The basic functions of the nervous system are provided by: • Sensory neurons • ...
System organization - PPM system types (Somatic, Autonomic & Enteric) and Reflex arc types
By: HWC, Views: 8526
• The PNS consists of all nervous tissue outside of the CNS. • It is divided into three functional components: • Somatic nervous system (SNS) • Autonomic nervous system (ANS) • Enteric nervous system (ENS) • The SNS consists of: • Sensory neurons from skeletal muscles ...
Requirements for nervous signals
By: HWC, Views: 8291
• The function of neurons is to allow communication between cells, thereby maintaining homeostasis. • Electrical signals, called membrane potentials, travel along the membranes of the neurons. • Voltage variability and distance traveled determine the type of nervous signal. 1. Graded...
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