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Pores and Ion Channels

By: HWC, Views: 6909

Transmembrane channels, also called membrane channels, are pores within a lipid bilayer. The channels can be formed by protein complexes that run across the membrane or by peptides. They may cross the cell membrane, connecting the cytosol, or cytoplasm, to the extracellular matrix. Membrane po...

Mechanisms of capillary exchange (transcytosis & bulk flow)

By: HWC, Views: 7399

■ This method of capillary exchange is mainly used to transport small amounts of large, lipid-insoluble (water soluble) molecules, such as large proteins. ■ Substances, packaged in vesicles, move through endothelial cells via endocytosis and exocytosis. ■ This method of exchange is th...

Major Elements in Biological Molecules: Proteins

By: HWC, Views: 7140

Proteins are chains of amino acids linked by peptide bonds. The 20 different amino acids used to make all proteins differ only in their side chains, and the properties of these side chains account for the great diversity of protein structure and function. Collagen is an example of how a prote...

The life cycle of protein

By: HWC, Views: 7354

The life cycle of a typical protein begins with its synthesis on a ribosome. As the polypeptide chain grows, molecules of a chaperone protein bind along its length. This prevents misfolding of the nascent polypeptide. ATP binding causes chaperone release. For most proteins, the polypeptide th...

Protein catabolism (Krebs cycle) and Protein anabolism (protein synthesis)

By: HWC, Views: 8173

• Deaminated acids are brought into the Krebs cycle to be oxidized to CO2 and H2O. • Before entering the Krebs cycle, the deaminated acids are converted into intermediate products (pyruvic acid, acetyl coenzyme A, carbonic acids). • In the Krebs cycle, amino acids are oxidized to form r...

Gastrin (protein digestion)

By: HWC, Views: 7731

The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after b...

Replication of DNA and Chromosomes/ How do cells replicate their DNA? (Animation) no Audio

By: HWC, Views: 7463

DNA replication in E. coil begins at a site called oriC where a replication bubble forms. At either end of this bubble is a replication fork. Since DNA polymerase Ill can read its DNA template strand only in the 3' to 5' direction this means that one strand (leading) can be read continuously b...

Protein Structure - Primary, Secondary, Tertiary and Quaternary

By: HWC, Views: 7656

A protein's first order structure, or primary structure, begins with the amino acid sequence of the polypeptide chain. The 20 different amino acids can be arranged in an infinite number of sequences. For example, the hormone insulin, which regulates the uptake of glucose from the blood into ce...

Digestive chemicals - water, gastric acid, bile & bicarbonate

By: HWC, Views: 7435

• Water is the most abundant molecule in ingested fluids. • Water plays a primary role in hydrolytic digestive reactions. • Helps liquefy and transport digestive foodstuffs down the tract. • Transports secretions from accessory digestive organs to gastrointestinal tract. • Aids ...