Gastrin (protein digestion)
Date Uploaded: 01/26/2020
The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after being affected by stimulus. • Hormone - the signaling chemical. • Target cell - a cell receptive to the hormone. • Action - what the cell does when affected by the hormone. • Response - the overall change in controlled body condition as a result of the feedback loop. • The gastric phase of digestion begins as the stomach fills with food (especially proteins). • Receptors sense distension and the increased gastric pH. • Stimulated receptors prompt G cells in mucosa of stomach to secrete gastrin. • Gastrin binds to parietal and chief cells in gastric mucosa. • Stimulated parietal cells produce more hydrochloric acid. • Chief cells produce more pepsinogen, the precursor to pepsin. • Increased pepsin and gastric acid increase the stomach's ability to digest proteins.
You must login to add videos to your playlists.