Gastrin (protein digestion)
Date Uploaded: 01/26/2020
Tags: homeworkclinic.com Homework Clinic HWC The endocrine system homeostasis circulatory system Gastrin (protein digestion) gastric pH gastric mucosa pepsinogen pepsin
The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after being affected by stimulus. • Hormone - the signaling chemical. • Target cell - a cell receptive to the hormone. • Action - what the cell does when affected by the hormone. • Response - the overall change in controlled body condition as a result of the feedback loop. • The gastric phase of digestion begins as the stomach fills with food (especially proteins). • Receptors sense distension and the increased gastric pH. • Stimulated receptors prompt G cells in mucosa of stomach to secrete gastrin. • Gastrin binds to parietal and chief cells in gastric mucosa. • Stimulated parietal cells produce more hydrochloric acid. • Chief cells produce more pepsinogen, the precursor to pepsin. • Increased pepsin and gastric acid increase the stomach's ability to digest proteins.
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