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hGH (protein synthesis, growth and development)

By: HWC, Views: 8102

• Increased GHRH, a hypothalamic releasing hormone stimulated by low blood glucose, physical exertion, and increased sympathetic stimulation, stimulates the production of human growth hormone (hGH) from the somatotrophic cells of the anterior pituitary. • Human growth hormone targets cartil...

Nucleic acid digestion -small intestine

By: HWC, Views: 7751

Nucleic acid digestion, which takes place in the small intestine, involves: • Pancreatic nucleases. • Brush-border enzymes in the small intestine. • Nucleic acids enter the small intestine dissolved in gastric chyme. • As gastric chyme enters the duodenum of the small intestine, p...

The life cycle of protein

By: HWC, Views: 7352

The life cycle of a typical protein begins with its synthesis on a ribosome. As the polypeptide chain grows, molecules of a chaperone protein bind along its length. This prevents misfolding of the nascent polypeptide. ATP binding causes chaperone release. For most proteins, the polypeptide th...

Factors that increase metabolic rate and heat production

By: HWC, Views: 7755

• All vital biochemical reactions are temperature dependent. • The overall rate at which metabolic reactions use energy is known as the metabolic rate. • Metabolic rate greatly determines body temperatures. • Temperature is maintained by balancing the loss of heat to the environment...

Oxygen - hemoglobin dissociation curve & Hemoglobin's affinity with oxygen - acidity

By: HWC, Views: 8349

• The partial pressure of oxygen is a primary factor influencing the degree of saturation of hemoglobin. • The Po2 determines the number of oxygen molecules that can bind or dissociate from hemoglobin. • Blood in vessels coming from the lungs is very high in Po2 so saturation is high. ...

Secretin (inhibiting gastric acid secretion), Cholecystokinin (fat digestion) & Cholecystokinin

By: HWC, Views: 7550

• As chyme approaches the small intestine, secretin also targets acid-producing parietal cells in the gastric mucosa. • Increased secretin inhibits gastric add secretion. • With less gastric acid produced, the chyme going into the intestine is less acidic. • The hormone CCK also reg...

Covalent bonds - role in the body

By: HWC, Views: 7700

A covalent bond is formed when atoms share one or more pairs of electrons. This is opposed to an ionic bond, where electrons are actually transferred from one atom to another. Formation • Atoms fill up the outer orbital by sharing electrons. • Two oxygen atoms sharing electrons form on...

Glycolysis - and oxygen

By: HWC, Views: 7982

The first reactions involve a single 6-carbon glucose sugar undergoing phosphorylation using two ATP molecules and resulting in two 3-carbon compounds. • The rest of this pathway involves an oxidation reduction reaction, forming two reduced coenzymes, and generation of four ATP molecules. ...

Nucleic acid digestion - brush border enzymes, end products & transport mechanism

By: HWC, Views: 7508

• Further digestion occurs at the microvilli (brush border) of the epithelial cells of the villi in the small intestine. • Two brush border enzymes complete nucleic acid digestion: • Phosphatases, which catalyze the cleavage of a phosphate to form a nucleoside (nitrogenous base and pent...