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Digestive chemicals - water, gastric acid, bile & bicarbonate

By: HWC, Views: 7432

• Water is the most abundant molecule in ingested fluids. • Water plays a primary role in hydrolytic digestive reactions. • Helps liquefy and transport digestive foodstuffs down the tract. • Transports secretions from accessory digestive organs to gastrointestinal tract. • Aids ...

Secretin (inhibiting gastric acid secretion), Cholecystokinin (fat digestion) & Cholecystokinin

By: HWC, Views: 7549

• As chyme approaches the small intestine, secretin also targets acid-producing parietal cells in the gastric mucosa. • Increased secretin inhibits gastric add secretion. • With less gastric acid produced, the chyme going into the intestine is less acidic. • The hormone CCK also reg...

Gastrin (gastric emptying) & Secretin (buffering gastric acid)

By: HWC, Views: 7242

• Gastrin also binds to the smooth muscle cells in the stomach causing: • Increased gastric motility. • Opening of pyloric sphincter. • Increased gastric emptying. • The intestinal phase of digestion begins as chyme enters the duodenum. • The chyme's acidity can damage int...

Digestive chemicals - types & enzymes

By: HWC, Views: 7706

• Chemical digestion breaks down food as it moves through the digestive tract. • Using enzymes and other digestive chemicals, the process reduces food particles into nutrient molecules that can be absorbed. • Most chemical digestion is done by the actions of digestive enzymes. • O...

Enzyme-Catalyzed Reactions

By: HWC, Views: 7180

S P Substrate in great excess ([S] -- [E]) (More correctly [S] -- KM, but more on this later) Zero order rate equation: v = k where k is the zero-order rate constant (with respect to substrate). (More correctly [S] -- KM, but more on this later) Substrate forms complex with enzyme. ...

Gastrin (protein digestion)

By: HWC, Views: 7730

The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after b...

Nucleic acid digestion -small intestine

By: HWC, Views: 7751

Nucleic acid digestion, which takes place in the small intestine, involves: • Pancreatic nucleases. • Brush-border enzymes in the small intestine. • Nucleic acids enter the small intestine dissolved in gastric chyme. • As gastric chyme enters the duodenum of the small intestine, p...

Virtual Enzyme Kinetics & Lineweaver Burk Plot

By: HWC, Views: 7299

• The double-reciprocal (also known as the Lineweaver-Burk) plot is created by plotting the inverse initial velocity (1/V0) as a function of the inverse of the substrate concentration (1/[S]). • This plot is a useful way to determined different inhibitors such as competitive, uncompetitive...

Mechanism of enzyme action

By: HWC, Views: 7592

■ The substrate makes contact with the active site. ■ A change in the shape of the enzyme occurs resulting in the transformation of the substrate. ■ A substrate may undergo decomposition, have its atoms rearranged, or two substrates may be synthesized. ■ The products of the reaction...