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Mechanisms for chromosome movement Animation

By: HWC, Views: 4868

At mitotic metaphase, the fully-formed spindle is composed of many microtubules that extend from the poles. Some of these, the kinetochore microtubules, are attached to the kinetochores of each chromosome. Kinetochores are located at the centromeres. At anaphase, sister chromatids separate and...

Chromosome structural organization/ Mechanisms for chromosome movement Animation

By: HWC, Views: 4039

How the chromosome is organized. At metaphase, the chromosomes are duplicated and are at their most condensed. In each chromosome, two identical sister chromatids are held together at a constricted region called the centromere. When a chromosome is condensed, interactions among chromosomal ...

Structure of a Ribosome

By: HWC, Views: 4760

The structure and function of the mammalian ribosome. The mammalian ribosome consists of two subunits, one small and one large. Each subunit is assembled in the nucleus from rRNA and structural proteins. Once assembled, the ribosomal subunits are shipped separately to the cytoplasm. ...

Power Supply Polyacrylamide Gel Protein Sample

By: HWC, Views: 7244

SDS-polyacrylamide gel electrophoresis is a powerful tool, which resolves proteins according to their molecular weights. Because proteins differ in size, shape, and charge, a protein sample is first denatured with the anionic detergent SDS. When the sample is heated, the SDS molecules bind to ...

Proteins

By: HWC, Views: 6933

Living things must accomplish a great number of tasks just to get through a day, and these tasks are accomplished by a diverse range of biological molecules. In the range of tasks that molecules accomplish, however, proteins reign supreme. Almost every chemical reaction that takes place in living...

The life cycle of protein

By: HWC, Views: 7526

The life cycle of a typical protein begins with its synthesis on a ribosome. As the polypeptide chain grows, molecules of a chaperone protein bind along its length. This prevents misfolding of the nascent polypeptide. ATP binding causes chaperone release. For most proteins, the polypeptide th...

Subunits of DNA And Semi Conservative Replication

By: HWC, Views: 4192

Adenine is a purine with a double-ring structure. In double-stranded DNA, adenine base-pairs with thymine. Guanine is a purine with a double-ring structure. In double-stranded DNA, guanine base-pairs with cytosine. Thymine is a pyrimidine with a single-ring structure. In double-stranded DNA, th...

Protein Structure - Primary, Secondary, Tertiary and Quaternary

By: HWC, Views: 7809

A protein's first order structure, or primary structure, begins with the amino acid sequence of the polypeptide chain. The 20 different amino acids can be arranged in an infinite number of sequences. For example, the hormone insulin, which regulates the uptake of glucose from the blood into ce...

Protein Secondary and Tertiary Structures - Animation

By: HWC, Views: 4060

Amino acid sequence dictates a protein's final shape. The presence of certain amino acids favors a pattern of hydrogen bonding that causes part of the polypeptide chain to coil and twist into an alpha helix. The presence of other amino acids enables hydrogen bonding between strand like r...