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Mechanism of enzyme action

By: HWC, Views: 7598

■ The substrate makes contact with the active site. ■ A change in the shape of the enzyme occurs resulting in the transformation of the substrate. ■ A substrate may undergo decomposition, have its atoms rearranged, or two substrates may be synthesized. ■ The products of the reaction...

Muscle cell structures - actin, myosin and titin filaments

By: HWC, Views: 7876

Once the muscle cell has been excited it will contract. • A muscle action potential will trigger the release Of Ca2+ ions into the sarcoplasm. • The Ca2+ ions bind to the regulatory proteins and trigger contraction. • Within skeletal muscle cells are structures that provide the ability...

Osmosis - water transport

By: HWC, Views: 7838

Osmosis is the flow of water down its concentration gradient, across a semi-permeable membrane. Osmosis is an example of diffusion, which is when molecules tend to distribute themselves evenly in a space. what is a semi-permeable membrane? It is a membrane or barrier that allows some molec...

Helper T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 7813

• Most cells which have CD4 on their surface become Helper T cells (TN cells). • The CD4 1 cells only recognize a foreign antigen when it is presented with an antigen presenting immune cell (APC) that includes MHC-II protein. • The Helper T cell antigen receptor must match the presented...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 8036

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

Polysaccharides

By: HWC, Views: 7312

More complex sugars are called polysaccharides (from "poly" meaning "many" and "saccharum" meaning "sugar"). Many things in nature are made of polysaccharides. Here we show one of the polysaccharides in corn, another in wood, and another in the exoskeletons of insects like grasshoppers. How are a...

Mechanisms of capillary exchange (transcytosis & bulk flow)

By: HWC, Views: 7399

■ This method of capillary exchange is mainly used to transport small amounts of large, lipid-insoluble (water soluble) molecules, such as large proteins. ■ Substances, packaged in vesicles, move through endothelial cells via endocytosis and exocytosis. ■ This method of exchange is th...

Glucose anabolism reactions: Glycogenolysis and Gluconeogenesis

By: HWC, Views: 8092

• Glucose not needed immediately is stored as glycogen. The process that creates it is glycogenesis. • When ATP is needed for body activities, stored glycogen is broken down by a process called glycogenolysis. • Glucose can be formed through two different anabolic reactions: • Glycog...

Acid-base imbalances - compensation of metabolic acidosis and alkalosis

By: HWC, Views: 7991

1. Metabolic acidosis: • Few HC03- ions are present so blood pH becomes acidic. • Compensation is increased respiratory rate and more CO2 is removed from the blood. • Blood pH returns to normal. 2. Metabolic alkalosis: • Many HC03- ions are present so blood pH becomes alkaline...