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Regulation of GFR: autoregulation via myogenic mechanism Myogenic mechanism

By: HWC, Views: 9199

• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Renal autoregulation occurs when...

Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation

By: HWC, Views: 8901

• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...

Factors that increase metabolic rate and heat production

By: HWC, Views: 7756

• All vital biochemical reactions are temperature dependent. • The overall rate at which metabolic reactions use energy is known as the metabolic rate. • Metabolic rate greatly determines body temperatures. • Temperature is maintained by balancing the loss of heat to the environment...

Enzyme-Catalyzed Reactions

By: HWC, Views: 7180

S P Substrate in great excess ([S] -- [E]) (More correctly [S] -- KM, but more on this later) Zero order rate equation: v = k where k is the zero-order rate constant (with respect to substrate). (More correctly [S] -- KM, but more on this later) Substrate forms complex with enzyme. ...

How do the different types of chromatography work? (No Audio)

By: HWC, Views: 7046

Chromatography is a term for a variety of techniques in which a mixture of dissolved components is fractionated as it moves through some type of porous matrix. A glass column is filled with beads of an inert matrix. The mixture of proteins to be purified is dissolved in a solution and passed ...

Effect of blood chemistry - stimuli, hyperventilation response and hypoventilation response

By: HWC, Views: 7442

• Respiratory rate is effected by changes in: • Blood pH. • Blood Pco2. • Blood P02. • Chemoreceptors in the central and peripheral nervous systems closely monitor the Fr, CO2 and 02 levels in blood. • Changes in frequency of impulses from Chemoreceptors affect respiratory r...

Depolarization of the SA node, Action potentials of the myocardium & ANS effects

By: HWC, Views: 7626

• A typical contractile cell in the myocardium has a resting membrane potential. • The resting membrane potential of cells in the SA node is not fixed, and is known as the pacemaker potential. • The action potential of a healthy SA nodal cell has three parts: • Pacemaker potential: ...

Michaelis–Menten equation & Kinetic parameters

By: HWC, Views: 7498

The Michaelis–Menten equation is the rate equation for a one-substrate enzyme-catalyzed reaction. This equation relates the initial reaction rate (v0), the maximum reaction rate (Vmax), and the initial substrate concentration [S] through the Michaelis constant KM—a measure of the substrat...

Exercise and cardiac output

By: HWC, Views: 7464

• Cardiac output: • Maintains blood flow throughout the body. • Measure of blood volume ejected from the heart over a given time. • Determined by multiplying heart rate by stroke volume (CO = SV x HR). • Heart rate: Number of beats/min. • Stroke volume: Amount of blood eject...