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Role of the urinary system - acidosis and alkalosis

By: HWC, Views: 7949

• Tubular cells of the proximal convoluted tubule and collecting tubules can alter filtrate pH and therefore blood pH. • These cells can affect blood pH with two coupled mechanisms: • Reabsorption of bicarbonate ions. • Secretion of hydrogen ions. • The reabsorption of bicarbonate...

Medullary osmotic gradient: countercurrent multiplier, urea recycling & vasa recta countercurrent exchange

By: HWC, Views: 8426

▪ The primary cause of the medullary osmotic gradient is the active transport of solutes. • In the ascending limb of the loop, active transport of Na+ ions drives passive reabsorption of Cl- ions. • Addition of these ions to the interstitial fluid of the medulla increases its osmolarity...

Medullary osmotic gradient - influencing factors

By: HWC, Views: 8058

▪ Maintenance of fluid volume and composition, despite changes in water input and output, is crucial to a healthy life. ▪ Regulation of blood's osmolarity, or solute concentration, is a function of the nephron. • Normal osmolarity is maintained by the ability of the nephron to alter uri...

ADH and the arterioles, kidneys, sweat glands and the Atrial natriuretic peptide (ANP)

By: HWC, Views: 7819

• ADH is also known as vasopressin. • Produced by hypothalmus and secreted by neurosecretory cells in posterior pituitary gland. • Responds to high blood osmotic pressure representing low amounts of water in the blood. • Binds to smooth muscle cells in walls of arterioles, stimulate...

Bulk flow - factors that influence bulk flow

By: HWC, Views: 7390

• Bulk flow helps regulate the relative volumes of blood and interstitial fluid. • Flow from blood to interstitium is called filtration. • Flow from interstitium to blood is called reabsorption. • Four factors determine the net direction of capillary exchange. • These factors in...

Bulk flow - Factors that influence bulk flow

By: HWC, Views: 7929

• Bulk flow helps regulate the relative volumes of blood and interstitial fluid. • Flow from blood to interstitium is called filtration. ■ Flow from interstitium to blood is called reabsorption. ■ Four factors determine the net direction of capillary exchange. ■ These factors in...

Acid-base imbalances - compensation of respiratory acidosis and alkalosis

By: HWC, Views: 7850

• When one pH balancing system is affected then the other balancing system attempts to correct, or compensate for, the pH imbalance. - Respiratory acidosis: • Excessive CO2 is present so blood pH becomes acidic. • Compensation is increased secretion of H+ into urine and reabsorption ...

Net filtration pressure and lymph formation, edema & blood velocity

By: HWC, Views: 7489

Bulk flow -net filtration pressure and lymph formation • The net filtration pressure (NFP) is the force promoting filtration minus the force promoting reabsorption. • At the arterial end of an ideal capillary, the filtration pressures are stronger. The result: net filtration. • At t...

Osmosis - water transport

By: HWC, Views: 7837

Osmosis is the flow of water down its concentration gradient, across a semi-permeable membrane. Osmosis is an example of diffusion, which is when molecules tend to distribute themselves evenly in a space. what is a semi-permeable membrane? It is a membrane or barrier that allows some molec...