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Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 7009

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Fermentation - When Oxygen Is Absent, Pyruvate to Lactate & Pyruvate to Ethanol

By: HWC, Views: 7298

Pyruvate is the end product of glycolysis. If oxygen is present, pyruvate enters the mitochondrion where further energy yielding reactions of the Krebs cycle will take place. However, if oxygen is not present, pyruvate will enter a pathway called fermentation. This pathway regenerates NAD+ fro...

Lactation and Breast Feeding

By: HWC, Views: 8548

Regulation of lactation - breast preparation • Pregnancy hormones trigger breast changes to prepare for feeding the new baby. • The amount of the hormone prolactin, essential to the initiation of lactation, increases steadily throughout pregnancy. • However, high levels of both estroge...

Ventilation - phases and driving forces

By: HWC, Views: 7803

Respiration is the exchange of gases between the atmosphere, blood, and cells The combination of 3 processes is required for respiration to occur Ventilation (breathing) External (pulmonary) respiration Internal (tissue) respiration The cardiovascular system assists the respiratory system b...

Stages of Mitosis - Prophase, Prometaphase, Metaphase, Anaphase & Telophase

By: HWC, Views: 7443

In mitosis, the nucleus divides to produce two nuclei that are genetically identical to each other and to the parent nucleus. To prepare for division, the DNA replicates in the preceding interphase. Although the chromosomes are not yet compacted and visible as discrete bodies, we illustrate them ...

Muscle cell structures - actin, myosin and titin filaments

By: HWC, Views: 7891

Once the muscle cell has been excited it will contract. • A muscle action potential will trigger the release Of Ca2+ ions into the sarcoplasm. • The Ca2+ ions bind to the regulatory proteins and trigger contraction. • Within skeletal muscle cells are structures that provide the ability...

Depolarization of the SA node, Action potentials of the myocardium & ANS effects

By: HWC, Views: 7633

• A typical contractile cell in the myocardium has a resting membrane potential. • The resting membrane potential of cells in the SA node is not fixed, and is known as the pacemaker potential. • The action potential of a healthy SA nodal cell has three parts: • Pacemaker potential: ...

Frequency of stimulation and force (Recruitment of motor units and force)

By: HWC, Views: 8063

• Muscle tension depends on the frequency of stimulation. • Muscle twitch: First stimulus. • Wave summation: When a second stimulus excites a partially relaxed muscle, producing a stronger contraction. • Unfused tetanus: Successive stimulations at the same frequency, producing a se...

Role of the respiratory system - effect of altered ventilation rates

By: HWC, Views: 7596

• Dissociation of the chemical substances in the body fluids can result in the production of free hydrogen ions. • The pH scale is used to measure the concentration of hydrogen ions in solution. • Normal blood pH values vary around 7.4. • When hydrogen ion concentration increases, t...