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Bulk flow - factors that influence bulk flow
By: HWC, Views: 8014
• Bulk flow helps regulate the relative volumes of blood and interstitial fluid. • Flow from blood to interstitium is called filtration. • Flow from interstitium to blood is called reabsorption. • Four factors determine the net direction of capillary exchange. • These factors in...
Mechanisms of capillary exchange (transcytosis & bulk flow)
By: HWC, Views: 8033
■ This method of capillary exchange is mainly used to transport small amounts of large, lipid-insoluble (water soluble) molecules, such as large proteins. ■ Substances, packaged in vesicles, move through endothelial cells via endocytosis and exocytosis. ■ This method of exchange is th...
Structures that affect circulation - kidneys, blood volume and venous tone
By: HWC, Views: 8315
• Kidneys regulate blood volume and blood osmolarity via salt and water reabsorption. • Increased reabsorption increases blood volume and venous return (and CO). • Decreased reabsorption increases urine production, which decreases blood volume and venous return (and CO). • Systemi...
Structures that affect circulation - heart and MABP
By: HWC, Views: 7922
■ BP is defined as the systolic BP over the diastolic BP. ■ MABP = diastolic BP + 1/3 (systolic BP - diastolic BP). ■ MABP accounts for diastole lasting longer than systole; mean is not equidistant between the two pressures.
By: HWC, Views: 8432
The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone after b...
Hormonal feedback loop components
By: HWC, Views: 8451
The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: ■ Stimulus - a change in a body condition. ■ Production cell - an endocrine cell that produces a hormone after b...
Stroke volume - contractility definition
By: HWC, Views: 7962
Contractility is the forcefulness of contraction of cardiac muscle. • Inotropic agents are substances that increase or decrease contractility (and stroke volume). • Positive inotropic agents increase contractility and will increase stroke volume and cardiac output. • Negative inotropi...
Structures that affect circulation - venous return
By: HWC, Views: 8195
• Venous return directly affects cardiac output. • Increased venous return leads directly to greater cardiac output whereas decreased return contributes to decreased output. • Venous return depends on: • Blood volume regulation by the kidneys. • Venous tone. • Skeletal muscl...
Structures that affect circulation - arterioles and vasomotor responses
By: HWC, Views: 8046
■ Small arteries and arterioles determine SVR. ■ Blood pressure drops significantly as blood passes through arterioles. ■ Decreasing arteriole radius and decreased wall elasticity are the main reasons for increased SVR. ■ Small changes in arteriole radius can cause large changes in ...
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