Bulk flow - factors that influence bulk flow

• Bulk flow helps regulate the relative volumes of blood and interstitial fluid. • Flow from blood to interstitium is called filtration. • Flow from interstitium to blood is called reabsorption. • Four factors determine the net direction of capillary exchange. • These factors include: • Blood hydrostatic pressure (BHP), which pushes fluid out of the capillary and promotes filtration. • Blood colloid osmotic pressure (BCOP), which acts as if it "pulls" fluid into the capillary and promotes reabsorption. • Interstitial fluid osmotic pressure (IFOP), which is the slight pull of fluids towards the interstitium promoting filtration. • Interstitial fluid hydrostatic pressure (IFHP), which is near zero under normal pressure

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