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Non-specific disease resistance mechanisms & Skin's defense barriers

By: HWC, Views: 6573

• Non-specific disease resistance acts quickly to fight a wide variety of invaders. • Mechanisms include: • Barriers • Antimicrobial substances • Cellular defenses • Inflammation • Fever Barriers - types • Physical and chemical bathers prevent invasion by micro...

Barriers - eye structures, digestive mucosa, respiratory mucosa & genitourinary mucosa

By: HWC, Views: 6887

• Eyebrows, eyelids, eyelashes and conjunctiva serve to trap microbes preventing their invasion. • Tearing (lacrimation) is a protective mechanism that washes away microbes that attempt to enter the eyes. • Salts, mucus, and lysozymes in tears neutralize substances and bacteria. â€...

Inflammation and Fever

By: HWC, Views: 7127

• Inflammation is an immune response that can occur anywhere in the body, but is observed most frequently on the skin. • It provides early protection by preventing infection from spreading to other parts of the body. • Inflammation also promotes repair of damaged tissues. Inflammat...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 6999

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

Cardiac conductile cells

By: HWC, Views: 6896

• In order for the heart to function properly, all of its cells must contract in a specific sequence. This sequence is determined by a pathway known as the conduction system. • Cardiac muscle cells have two attributes that enable the conduction system to work: • Connective. Action pot...

Coaductile pathway, Timing of contraction signal & Conduction system and ECG

By: HWC, Views: 6880

• When the system is healthy, the signal to contract the entire conduction system originates in the SA node - known as the heart's pacemaker. • The SA node triggers contraction because it depolarizes at a faster rate than other parts of the conduction system. • The wave of excitation fr...

Depolarization of the SA node, Action potentials of the myocardium & ANS effects

By: HWC, Views: 6517

• A typical contractile cell in the myocardium has a resting membrane potential. • The resting membrane potential of cells in the SA node is not fixed, and is known as the pacemaker potential. • The action potential of a healthy SA nodal cell has three parts: • Pacemaker potential: ...

Electrical changes in the heart

By: HWC, Views: 6484

• ECG: Graph of the voltage changes that occur during the cardiac cycle. • Readings are taken by electrodes placed on the surface of the body. • Electrodes detect voltage changes caused by the electrical activity of the heart. • P wave = atrial excitation (atrial depolarization). ...

Heart sounds

By: HWC, Views: 6517

During a normal, healthy heartbeat, or what we call a cardiac cycle, the top two chambers of the heart, called the atria, contract simultaneously. Then, as they relax, the bottom two chambers, called the ventricles, contract. This explains what happens during a cardiac cycle, but what it doesn't ...