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Role of complement proteins

By: HWC, Views: 6790

• Non-specific and specific defense mechanisms work through the functions of complement proteins. • As soon as pathogens penetrate the physical barrier of the skin, other resistance mechanisms begin. • Cells, such as macrophages, phagocytize pathogens. • These cells increase exposu...

Primary and secondary response to infection

By: HWC, Views: 6718

• Pathogens enter the body by penetrating the non-specific barriers in the skin and mucus membranes. • Pathogens first encounter macrophages and natural killer cells that carry out phagocytosis and cytolysis respectively. • A pathogen's first encounter with the immune system can promo...

Non-specific disease resistance mechanisms & Skin's defense barriers

By: HWC, Views: 6894

• Non-specific disease resistance acts quickly to fight a wide variety of invaders. • Mechanisms include: • Barriers • Antimicrobial substances • Cellular defenses • Inflammation • Fever Barriers - types • Physical and chemical bathers prevent invasion by micro...

Barriers - eye structures, digestive mucosa, respiratory mucosa & genitourinary mucosa

By: HWC, Views: 7221

• Eyebrows, eyelids, eyelashes and conjunctiva serve to trap microbes preventing their invasion. • Tearing (lacrimation) is a protective mechanism that washes away microbes that attempt to enter the eyes. • Salts, mucus, and lysozymes in tears neutralize substances and bacteria. â€...

Types of antimicrobial substances (interferons & complement protein)

By: HWC, Views: 7035

• Found in blood and interstitial fluids. • Discourage microbial growth. • Include interferon and complement proteins. • Produced and released by virus-infected lymphocytes. • Enter new cells and inhibit viral replication. • Act against a large variety of viruses (non-speci...

Cellular defenses (natural killer cells, phagocyte types & process of phagocytosis)

By: HWC, Views: 6774

• Lymphocytes that rapidly defend against abnormal (cancer) or virus-infected cells. • Found in blood, spleen, lymph nodes, and red bone marrow. • Lack receptors for binding with specific antigens. • Act upon cells displaying abnormal MHC antigens. • NK cells destroy cells in ...

Inflammation and Fever

By: HWC, Views: 7432

• Inflammation is an immune response that can occur anywhere in the body, but is observed most frequently on the skin. • It provides early protection by preventing infection from spreading to other parts of the body. • Inflammation also promotes repair of damaged tissues. Inflammat...

Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 7289

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

B cells and antibodies

By: HWC, Views: 7771

What Are Antibodies? Antibodies, also known as immunoglobulins, are Y-shaped proteins that are produced by the immune system to help stop intruders from harming the body. When an intruder enters the body, the immune system springs into action. These invaders, which are called antigens, can be vi...