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Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation

By: HWC, Views: 8898

• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...

ADH and the arterioles, kidneys, sweat glands and the Atrial natriuretic peptide (ANP)

By: HWC, Views: 7818

• ADH is also known as vasopressin. • Produced by hypothalmus and secreted by neurosecretory cells in posterior pituitary gland. • Responds to high blood osmotic pressure representing low amounts of water in the blood. • Binds to smooth muscle cells in walls of arterioles, stimulate...

Regulation of GFR: autoregulation via myogenic mechanism Myogenic mechanism

By: HWC, Views: 9194

• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Renal autoregulation occurs when...

Carbohydrate Metabolism: Introduction to renal processes and filtrate formation and composition

By: HWC, Views: 7899

• At the nephron, the three process responsible for the formation of urine include: • Glomerular filtration. • Tubular reabsorption. • Tubular secretion. • During filtration, a filtrate is formed within the renal tubule. • Reabsorption is the conserving of water and many s...

Role of the urinary system - acidosis and alkalosis

By: HWC, Views: 7948

• Tubular cells of the proximal convoluted tubule and collecting tubules can alter filtrate pH and therefore blood pH. • These cells can affect blood pH with two coupled mechanisms: • Reabsorption of bicarbonate ions. • Secretion of hydrogen ions. • The reabsorption of bicarbonate...

Regulation of GFR: three methods, autoregulation & autoregulation via myogenic mechanism

By: HWC, Views: 8155

• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Hormonal regulation. • Ren...

Atrial natriuretic peptide (vasodilation) & Aldosterone

By: HWC, Views: 7348

• Certain situations will cause the body's stress level to rise. • increased blood pressure will stretch the atria of the heart, stimulating the secretion of atria natriuretic peptide (MP). • ANP causes muscle cells in blood vessels to relax. • Blood pressure is lowered as a result ...

Renin/Angiotensin (water gain from urine & Na ion and water reabsorption)

By: HWC, Views: 7647

• Sensing declining blood pressure or blood volume, juxtaglomerular cells of the nephron release renin, an enzyme that promotes the formation of angiotensin II. • Angiotensin II targets smooth muscle cells in blood vessels that provide blood to the nephron. • Angiotensin II causes thes...

Medullary osmotic gradient: countercurrent multiplier, urea recycling & vasa recta countercurrent exchange

By: HWC, Views: 8426

▪ The primary cause of the medullary osmotic gradient is the active transport of solutes. • In the ascending limb of the loop, active transport of Na+ ions drives passive reabsorption of Cl- ions. • Addition of these ions to the interstitial fluid of the medulla increases its osmolarity...