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Mechanisms of capillary exchange

By: HWC, Views: 7895

■ The primary role of capillaries is to permit the exchange of nutrients and wastes between the blood and tissue cells (via interstitial fluid). ■ Oxygen and nutrients move from the blood to the cells. ■ Carbon dioxide and other wastes move from the cells to the blood. The three ba...

Bulk flow - Factors that influence bulk flow

By: HWC, Views: 7946

• Bulk flow helps regulate the relative volumes of blood and interstitial fluid. • Flow from blood to interstitium is called filtration. ■ Flow from interstitium to blood is called reabsorption. ■ Four factors determine the net direction of capillary exchange. ■ These factors in...

The primary factors that affect circulation - MABP, CO and SVR

By: HWC, Views: 8072

Introduction Blood flow is determined by the relative intensities of factors that drive and resist moving blood. • Cardiac output (CO) equals the mean arterial blood pressure (MABP, a driving force) divided by systemic vascular resistance (SVR, a resisting force). • Hormones and the cen...

Structures that affect circulation - heart and systolic/diastolic BP

By: HWC, Views: 7668

• Heart generates blood pressure. • Arterioles produce resistance thereby regulating blood flow to tissues. • Veins store blood; kidneys regulate blood volume; both affect venous return and cardiac output. ■ Contractions of the ventricles determine blood pressure, which drives th...

Structures that affect circulation - arterioles and vasomotor responses and venous return

By: HWC, Views: 7813

■ Small arteries and arterioles determine SVR. • Blood pressure drops significantly as blood passes through arterioles. • Decreasing arteriole radius and decreased wall elasticity are the main reasons for increased SVR. ■ Small changes in arteriole radius can cause large changes in ...

Structures that affect circulation - kidneys and blood volume and skeletal muscle pumping

By: HWC, Views: 8312

• Kidneys regulate blood volume and blood osmolarity via salt and water reabsorption. • Increased reabsorption increases blood volume and venous return (and CO). • Decreased reabsorption Increases urine production, which decreases blood volume and venous return (and CO). • Systemi...

Neural regulation of blood pressure - baroreceptor and chemoreceptor reflexes

By: HWC, Views: 8009

• The nervous system regulates blood pressure with two reflex arcs: baroreceptor and chemoreceptor. ■ Baroreceptors (pressure) and chemoreceptors (chemical) are located in the carotid sinus and aortic arch. • Carotid sinus reflex helps maintain normal blood pressure in brain. • Ba...

Hormonal regulation of blood pressure - RAA system

By: HWC, Views: 8174

■ Long-term regulation of MABP is under hormonal control. • Hormones that affect blood pressure and volume: the renin-angiotensin-aldosterone (RAA) system, antidiuretic hormone (ADM), and atrial natriuretic peptide (ANP). ■ Most important hormonal regulator of MABP. Activated by drop in...

Angiotensin II - kidneys, adrenal glands and dehydration

By: HWC, Views: 7873

• Angiontensin II targets cells in the proximal convoluted tubule of the nephron. ■ The reabsorption of Na+ and Cl- ions sets up an osmotic gradient favoring the retention of water. • Decreases urine production and increases blood volume and pressure. • Angiontensin II targets zon...