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Normal and abnormal blood pH

By: HWC, Views: 7796

• Dissociation of the chemical substances in the body fluids can result in the production of free hydrogen ions. • The pH scale is used to measure the concentration of hydrogen ions in solution. • Normal blood pH values vary around 7.4. • When hydrogen ion concentration increases, t...

Simple Diffusion - Ion transport

By: HWC, Views: 7770

In the process of diffusion, a substance tends to move from an area of high concentration to an area of low concentration until its concentration becomes equal throughout a space. Ions must diffuse through membrane pores or gated channels. Pores are always open. More pores allow more ions...

Muscle cell structures - actin, myosin and titin filaments

By: HWC, Views: 7894

Once the muscle cell has been excited it will contract. • A muscle action potential will trigger the release Of Ca2+ ions into the sarcoplasm. • The Ca2+ ions bind to the regulatory proteins and trigger contraction. • Within skeletal muscle cells are structures that provide the ability...

Acid-base imbalances - compensation of metabolic acidosis and alkalosis

By: HWC, Views: 8021

1. Metabolic acidosis: • Few HC03- ions are present so blood pH becomes acidic. • Compensation is increased respiratory rate and more CO2 is removed from the blood. • Blood pH returns to normal. 2. Metabolic alkalosis: • Many HC03- ions are present so blood pH becomes alkaline...

Renin/Angiotensin (water gain from urine & Na ion and water reabsorption)

By: HWC, Views: 7670

• Sensing declining blood pressure or blood volume, juxtaglomerular cells of the nephron release renin, an enzyme that promotes the formation of angiotensin II. • Angiotensin II targets smooth muscle cells in blood vessels that provide blood to the nephron. • Angiotensin II causes thes...

Nervous pathway to the Neuromuscular (NMJ)

By: HWC, Views: 8291

• A nervous impulse, also called an action potential, starts from the brain or spinal cord to signal skeletal muscle cell contraction. Action potentials continue along a motor neuron to the muscle cell. • The signal to contract must cross a synapse - the neuromuscular junction (NMJ) - betwe...

Acid-base imbalances - compensation of respiratory acidosis and alkalosis

By: HWC, Views: 7868

• When one pH balancing system is affected then the other balancing system attempts to correct, or compensate for, the pH imbalance. - Respiratory acidosis: • Excessive CO2 is present so blood pH becomes acidic. • Compensation is increased secretion of H+ into urine and reabsorption ...

Primary Active Transport - electrochemical gradient and ion transport / water movement

By: HWC, Views: 7858

Energy derived from ATP changes the shape of a transporter protein which pumps a substance across a plasma membrane against its concentration gradient An electrochemical gradient is a gradient of electrochemical potential, usually for an ion that can move across a membrane. The gradient consis...

Graded potentials - electrical characteristics and types

By: HWC, Views: 8000

• A graded potential occurs when a gated channel is opened or closed, altering ion flow through the membrane. • Changes in ion and charge distributions cause voltage changes to the resting membrane potential. • The strength of the stimulus determines the number of gated channels affect...