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Oxygen transport: association and dissociation & Factors that affect hemoglobin's saturation with O2

By: HWC, Views: 8280

• The production of oxyhemoglobin can be illustrated through the following reaction: 02 + Hb-H --) Hb-02 + H+ • This equation represents the binding of oxygen to the iron ions in heme groups in hemoglobin molecules. • Oxygen binding or loading occurs at the lungs • The dissociatio...

Oxygen - hemoglobin dissociation curve & Hemoglobin's affinity with oxygen - acidity

By: HWC, Views: 8991

• The partial pressure of oxygen is a primary factor influencing the degree of saturation of hemoglobin. • The Po2 determines the number of oxygen molecules that can bind or dissociate from hemoglobin. • Blood in vessels coming from the lungs is very high in Po2 so saturation is high. ...

Hemoglobin's affinity with oxygen - carbon dioxide, temperature and bisphosphoglycerate (BPG)

By: HWC, Views: 8441

• The carbon dioxide gas is temporarily converted to carbonic acid in red blood cells by the enzyme carbonic anhydrase, and then further converted to hydrogen and bicarbonate ions. • The result of increased carbon dioxide is decreased pH causing the Bohr effect. • Elevated carbon dioxid...

Methods of carbon dioxide transport - carbaminohemoglobin and bicarbonate ions

By: HWC, Views: 8418

• Carbon dioxide is transported three ways: • As bicarbonate ions in the plasma. • Bound to hemoglobin. • As a dissolved gas in the plasma. • A small percent of carbon dioxide is transported as a dissolved gas. • Some of the carbon dioxide is bound to hemoglobin, in the fo...

Basic rhythm - control centers in medulla oblongata, spirograph and normal tidal cycle

By: HWC, Views: 8203

• Normal ventilation is rhythmic and involves continuous cycles of inspiration and expiration. • Various regions of the brain closely regulate this rhythmic pattern of ventilation. • The rhythmicity area in the medulla regulates the basic rhythm of ventilation. • The medullary rhy...

Control of ventilation rate by other brain centers (posts, hypothalamus & cerebral cortex)

By: HWC, Views: 8336

Forced ventilation: • The inspiratory area stimulates accessory inspiratory muscles. • Inspiration is more forceful. • Inspiratory area activates expiratory area, which sends impulses to the expiratory muscles (internal intercostals and abdominal muscles). • Expiration muscles c...

Effect of blood chemistry - stimuli, hyperventilation response and hypoventilation response

By: HWC, Views: 8030

• Respiratory rate is effected by changes in: • Blood pH. • Blood Pco2. • Blood P02. • Chemoreceptors in the central and peripheral nervous systems closely monitor the Fr, CO2 and 02 levels in blood. • Changes in frequency of impulses from Chemoreceptors affect respiratory r...

Role of the respiratory system - effect of altered ventilation rates

By: HWC, Views: 8254

• Dissociation of the chemical substances in the body fluids can result in the production of free hydrogen ions. • The pH scale is used to measure the concentration of hydrogen ions in solution. • Normal blood pH values vary around 7.4. • When hydrogen ion concentration increases, t...

Introduction to filtration - filtrate formation and composition

By: HWC, Views: 8570

• At the nephron, the three process responsible for the formation of urine include: • Glomerular filtration. • Tubular reabsorption. • Tubular secretion. • During filtration, a filtrate is formed within the renal tubule. • Reabsorption is the conserving of water and many s...