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The life cycle of protein

By: HWC, Views: 6226

The life cycle of a typical protein begins with its synthesis on a ribosome. As the polypeptide chain grows, molecules of a chaperone protein bind along its length. This prevents misfolding of the nascent polypeptide. ATP binding causes chaperone release. For most proteins, the polypeptide th...

Hormonal regulation of pregnancy - weeks 17 through 38

By: HWC, Views: 6918

• Estrogens increase uterine blood flow, maintaining the endometrium during pregnancy. • High levels of estrogen and progesterone inhibit the synthesis of milk. Progesterone inhibits myometrial contractions of the uterus to prevent premature birth. • Relaxin inhibits myometrial contract...

New DNA Strand Replication

By: HWC, Views: 6140

First step: strands are separated • Helicase unwinds the DNA double helix at the replication fork • SSBs coat the single strands to prevent reannealing • Polymerase attaches nucleotide at 3' end • Synthesis is in 5' to 3' direction DNA Polymerase: • Only extends nucleic ac...

Status Epilepticus

By: Administrator, Views: 9646

Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. Previous definitions used a 30-minute time limit. The seizures can be of the tonic–clonic type, with a re...

Proteins

By: HWC, Views: 5683

Living things must accomplish a great number of tasks just to get through a day, and these tasks are accomplished by a diverse range of biological molecules. In the range of tasks that molecules accomplish, however, proteins reign supreme. Almost every chemical reaction that takes place in living...

Lipid catabolism - lipolysis and beta oxidation and oxidation of fatty acids

By: HWC, Views: 6920

• Digestion hydrolyzes lipids into fatty acids and glycerol. • Fatty acids and glycerol are: • Oxidized to generate ATP. • Used to produce triglycerides that are stored as energy reserves in adipose tissue. • Lipid catabolism begins with lipolysis in which lipids are broken do...

Hemoglobin's affinity with oxygen - carbon dioxide, temperature and bisphosphoglycerate (BPG)

By: HWC, Views: 6793

• The carbon dioxide gas is temporarily converted to carbonic acid in red blood cells by the enzyme carbonic anhydrase, and then further converted to hydrogen and bicarbonate ions. • The result of increased carbon dioxide is decreased pH causing the Bohr effect. • Elevated carbon dioxid...

Cellular Defects - Osteoblasts, Osteoclasts and Osteocytes

By: HWC, Views: 6320

■ Metabolically active bone-building cells that secrete astroid. ■ Cover surfaces of newly formed bone and respond to growth stimuli ■ Less responsive to growth factors as the body ages. ■ Contribute to hone loss once their reproductive and biosynthetic potential lessens....

Red Blood Cells - Erythropoietin (EPO)

By: HWC, Views: 6680

• The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone aft...