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Mechanism of enzyme action

By: HWC, Views: 9778

■ The substrate makes contact with the active site. ■ A change in the shape of the enzyme occurs resulting in the transformation of the substrate. ■ A substrate may undergo decomposition, have its atoms rearranged, or two substrates may be synthesized. ■ The products of the reaction...

Lipid catabolism ( ketogenesis and oxidation of glycerol) and Lipid anabolism (lipogenesis)

By: HWC, Views: 10240

• During excessive beta oxidation, the two-carbon fatty acid fragments are converted into acidic ketone bodies. • Ketosis, the overproduction of ketone bodies, can lead to acidosis (ketoacidosis) of the blood. • After lipolysis, glycerol is converted to pyruvic acid. • Pyruvic aci...

Hormones and the menstrual cycle Animation

By: HWC, Views: 6910

Feedback loops to the hypothalamus and pituitary gland from the ovaries during the menstrual cycle Animation for a step-by-step explanation. Production of a releasing hormone (GnRH) by the hypothalamus prods the pituitary's anterior lobe to release FSH and LH. In the ovary, FSH and LH stimula...

ATPase function - membrane transport, contractile proteins and synthesis

By: HWC, Views: 10338

• Energy from ATP is used to move ions across the cell membrane during active transport. • This membrane protein transports sodium out of the cell and potassium into the cell. As such, it is called a sodium-potassium pump. • Because this pump also acts as an enzyme to hydrolyze ATP it i...

Role of the urinary system - acidosis and alkalosis

By: HWC, Views: 10127

• Tubular cells of the proximal convoluted tubule and collecting tubules can alter filtrate pH and therefore blood pH. • These cells can affect blood pH with two coupled mechanisms: • Reabsorption of bicarbonate ions. • Secretion of hydrogen ions. • The reabsorption of bicarbonate...

Phases of the Female Reproductive Cycle - Hormonal regulation

By: HWC, Views: 10431

FSH, LH and estrogen • FSH travels through the bloodstream from the anterior pituitary to the ovaries. • FSH promotes follicular growth. Increased follicular growth promotes estrogen production. • Small increases in blood estrogen levels inhibit the release of FSH and LH into the bl...

Hormonal regulation of pregnancy - weeks 17 through 38

By: HWC, Views: 10209

• Estrogens increase uterine blood flow, maintaining the endometrium during pregnancy. • High levels of estrogen and progesterone inhibit the synthesis of milk. Progesterone inhibits myometrial contractions of the uterus to prevent premature birth. • Relaxin inhibits myometrial contract...

Power Supply Polyacrylamide Gel Protein Sample

By: HWC, Views: 9258

SDS-polyacrylamide gel electrophoresis is a powerful tool, which resolves proteins according to their molecular weights. Because proteins differ in size, shape, and charge, a protein sample is first denatured with the anionic detergent SDS. When the sample is heated, the SDS molecules bind to ...

Definition of heart rate

By: HWC, Views: 10059

• Heart rate is determined by the rate of depolarizations of the sinoatrial (SA) node. • Cardiac output is directly proportional to heart rate, the greater the heart rate the greater the cardiac output. • Changes in heart rate are associated with exercise, stress or injury. Nervous ...