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Oxygen - hemoglobin dissociation curve & Hemoglobin's affinity with oxygen - acidity

By: HWC, Views: 8373

• The partial pressure of oxygen is a primary factor influencing the degree of saturation of hemoglobin. • The Po2 determines the number of oxygen molecules that can bind or dissociate from hemoglobin. • Blood in vessels coming from the lungs is very high in Po2 so saturation is high. ...

Hemoglobin's affinity with oxygen - carbon dioxide, temperature and bisphosphoglycerate (BPG)

By: HWC, Views: 7834

• The carbon dioxide gas is temporarily converted to carbonic acid in red blood cells by the enzyme carbonic anhydrase, and then further converted to hydrogen and bicarbonate ions. • The result of increased carbon dioxide is decreased pH causing the Bohr effect. • Elevated carbon dioxid...

Methods of carbon dioxide transport - carbaminohemoglobin and bicarbonate ions

By: HWC, Views: 7798

• Carbon dioxide is transported three ways: • As bicarbonate ions in the plasma. • Bound to hemoglobin. • As a dissolved gas in the plasma. • A small percent of carbon dioxide is transported as a dissolved gas. • Some of the carbon dioxide is bound to hemoglobin, in the fo...

Basic rhythm - control centers in medulla oblongata, spirograph and normal tidal cycle

By: HWC, Views: 7597

• Normal ventilation is rhythmic and involves continuous cycles of inspiration and expiration. • Various regions of the brain closely regulate this rhythmic pattern of ventilation. • The rhythmicity area in the medulla regulates the basic rhythm of ventilation. • The medullary rhy...

Effect of blood chemistry - stimuli, hyperventilation response and hypoventilation response

By: HWC, Views: 7459

• Respiratory rate is effected by changes in: • Blood pH. • Blood Pco2. • Blood P02. • Chemoreceptors in the central and peripheral nervous systems closely monitor the Fr, CO2 and 02 levels in blood. • Changes in frequency of impulses from Chemoreceptors affect respiratory r...

Role of the respiratory system - effect of altered ventilation rates

By: HWC, Views: 7601

• Dissociation of the chemical substances in the body fluids can result in the production of free hydrogen ions. • The pH scale is used to measure the concentration of hydrogen ions in solution. • Normal blood pH values vary around 7.4. • When hydrogen ion concentration increases, t...

Introduction to filtration - filtrate formation and composition

By: HWC, Views: 7933

• At the nephron, the three process responsible for the formation of urine include: • Glomerular filtration. • Tubular reabsorption. • Tubular secretion. • During filtration, a filtrate is formed within the renal tubule. • Reabsorption is the conserving of water and many s...

Regulation of GFR: three methods, autoregulation & autoregulation via myogenic mechanism

By: HWC, Views: 8182

• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Hormonal regulation. • Ren...

Regulation of GFR: autoregulation via tubuloglomerular feedback, neural & hormonal regulation

By: HWC, Views: 8921

• When blood pressure is above normal, rapid filtrate flow reduces ion retention so filtrate in tubule has more Na+, C1-, and water. • It is believed that vasoconstricting chemicals from the juxtaglomerular cells are released when the macula densa cells detect higher water and ion levels in ...