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Pores and Ion Channels

By: HWC, Views: 6907

Transmembrane channels, also called membrane channels, are pores within a lipid bilayer. The channels can be formed by protein complexes that run across the membrane or by peptides. They may cross the cell membrane, connecting the cytosol, or cytoplasm, to the extracellular matrix. Membrane po...

The life cycle of protein

By: HWC, Views: 7352

The life cycle of a typical protein begins with its synthesis on a ribosome. As the polypeptide chain grows, molecules of a chaperone protein bind along its length. This prevents misfolding of the nascent polypeptide. ATP binding causes chaperone release. For most proteins, the polypeptide th...

Hormonal regulation of pregnancy - weeks 17 through 38

By: HWC, Views: 7975

• Estrogens increase uterine blood flow, maintaining the endometrium during pregnancy. • High levels of estrogen and progesterone inhibit the synthesis of milk. Progesterone inhibits myometrial contractions of the uterus to prevent premature birth. • Relaxin inhibits myometrial contract...

Status Epilepticus

By: Administrator, Views: 10708

Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. Previous definitions used a 30-minute time limit. The seizures can be of the tonic–clonic type, with a re...

Fermentation - When Oxygen Is Absent, Pyruvate to Lactate & Pyruvate to Ethanol

By: HWC, Views: 7279

Pyruvate is the end product of glycolysis. If oxygen is present, pyruvate enters the mitochondrion where further energy yielding reactions of the Krebs cycle will take place. However, if oxygen is not present, pyruvate will enter a pathway called fermentation. This pathway regenerates NAD+ fro...

Proteins

By: HWC, Views: 6770

Living things must accomplish a great number of tasks just to get through a day, and these tasks are accomplished by a diverse range of biological molecules. In the range of tasks that molecules accomplish, however, proteins reign supreme. Almost every chemical reaction that takes place in living...

Hemoglobin's affinity with oxygen - carbon dioxide, temperature and bisphosphoglycerate (BPG)

By: HWC, Views: 7811

• The carbon dioxide gas is temporarily converted to carbonic acid in red blood cells by the enzyme carbonic anhydrase, and then further converted to hydrogen and bicarbonate ions. • The result of increased carbon dioxide is decreased pH causing the Bohr effect. • Elevated carbon dioxid...

Cellular Defects - Osteoblasts, Osteoclasts and Osteocytes

By: HWC, Views: 7324

■ Metabolically active bone-building cells that secrete astroid. ■ Cover surfaces of newly formed bone and respond to growth stimuli ■ Less responsive to growth factors as the body ages. ■ Contribute to hone loss once their reproductive and biosynthetic potential lessens....

Red Blood Cells - Erythropoietin (EPO)

By: HWC, Views: 7711

• The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone aft...