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Structures that affect circulation - arterioles and vasomotor responses and venous return
By: HWC, Views: 7818
■ Small arteries and arterioles determine SVR. • Blood pressure drops significantly as blood passes through arterioles. • Decreasing arteriole radius and decreased wall elasticity are the main reasons for increased SVR. ■ Small changes in arteriole radius can cause large changes in ...
Bond types - Atomic structure and basis of bonds
By: HWC, Views: 8134
• Chemical bonds are fundamental to the structure and function of many types of molecules, such as proteins, carbohydrates, lipids, nucleic acids, gases, salts and water. ■ These molecules are composed of atoms that are held together by three different types of bonds. • The three types ...
ATPase function - membrane transport, contractile proteins and synthesis
By: HWC, Views: 8122
• Energy from ATP is used to move ions across the cell membrane during active transport. • This membrane protein transports sodium out of the cell and potassium into the cell. As such, it is called a sodium-potassium pump. • Because this pump also acts as an enzyme to hydrolyze ATP it i...
Carbohydrate Metabolism: Introduction to renal processes and filtrate formation and composition
By: HWC, Views: 7935
• At the nephron, the three process responsible for the formation of urine include: • Glomerular filtration. • Tubular reabsorption. • Tubular secretion. • During filtration, a filtrate is formed within the renal tubule. • Reabsorption is the conserving of water and many s...
Glomerubular filtrate rate -pressures that affect GFR and net filtration pressure
By: HWC, Views: 8203
• The glomerular filtration rate is the amount of filtrate formed per minute within the renal corpuscle. • Once the filtrate is formed it moves down the tubule. • The production and movement of filtrate depends on three pressures: I. Glomerular blood hydrostatic pressure (GBHP) is pre...
Regulation of GFR: autoregulation via myogenic mechanism Myogenic mechanism
By: HWC, Views: 9216
• GFR can be regulated by adjusting: • Blood flow in and out of the glomerular capillaries. • Surface area of glomerular capillaries. • There are three main ways to make these adjustments: • Renal autoregulation. • Nervous regulation. • Renal autoregulation occurs when...
Lipid catabolism - lipolysis and beta oxidation and oxidation of fatty acids
By: HWC, Views: 8007
• Digestion hydrolyzes lipids into fatty acids and glycerol. • Fatty acids and glycerol are: • Oxidized to generate ATP. • Used to produce triglycerides that are stored as energy reserves in adipose tissue. • Lipid catabolism begins with lipolysis in which lipids are broken do...
Lipid catabolism ( ketogenesis and oxidation of glycerol) and Lipid anabolism (lipogenesis)
By: HWC, Views: 8058
• During excessive beta oxidation, the two-carbon fatty acid fragments are converted into acidic ketone bodies. • Ketosis, the overproduction of ketone bodies, can lead to acidosis (ketoacidosis) of the blood. • After lipolysis, glycerol is converted to pyruvic acid. • Pyruvic aci...
Factors that increase metabolic rate and heat production
By: HWC, Views: 7790
• All vital biochemical reactions are temperature dependent. • The overall rate at which metabolic reactions use energy is known as the metabolic rate. • Metabolic rate greatly determines body temperatures. • Temperature is maintained by balancing the loss of heat to the environment...
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